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2-methylisocitrate lyase activity

Known as: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming), methylisocitrate lyase activity, MICL 
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate. [EC:4.1.3.30, RHEA:16812]
National Institutes of Health

Papers overview

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2017
2017
The alternative sigma factor σE is a key component of the Escherichia coli response to cell envelope stress and is required for… Expand
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2016
2016
BACKGROUND Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed… Expand
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Highly Cited
2014
Highly Cited
2014
In enteric bacteria, the transcription factor σ(E) maintains membrane homeostasis by inducing synthesis of proteins involved in… Expand
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2013
2013
IntroductionMonosodium urate crystals (MSU), the etiological agent of gout, are one of the most potent proinflammatory stimuli… Expand
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2008
2008
Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis… Expand
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2006
2006
C-type lectins are the most diverse and prevalent lectin family in immunity. Particular interest has recently been attracted by… Expand
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2006
2006
Phosphonopyruvate (P-pyr) hydrolase (PPH), a member of the phosphoenolpyruvate (PEP) mutase/isocitrate lyase (PEPM/ICL… Expand
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Highly Cited
2004
Highly Cited
2004
Inhibitory and activatory C-type lectin-like receptors play an important role in immunity through the regulation of leukocytes… Expand
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Highly Cited
2000
Highly Cited
2000
The Saccharomyces cerevisiae ICL1 gene encodes isocitrate lyase, an essential enzyme for growth on ethanol and acetate. Previous… Expand
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1975
1975
A rapid focus-induction assay has been developed for certain replicating (r+) but nontransforming (t−) mammalian type C viruses… Expand
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