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2-methylisocitrate lyase activity

Known as: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming), methylisocitrate lyase activity, MICL 
Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate. [EC:4.1.3.30, RHEA:16812]
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Lectins recognize a diverse array of carbohydrate structures and perform numerous essential biological functions. Here we focus… Expand
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Highly Cited
2014
Highly Cited
2014
In enteric bacteria, the transcription factor σ(E) maintains membrane homeostasis by inducing synthesis of proteins involved in… Expand
2013
2013
IntroductionMonosodium urate crystals (MSU), the etiological agent of gout, are one of the most potent proinflammatory stimuli… Expand
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Highly Cited
2008
Highly Cited
2008
Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis… Expand
Review
2007
Review
2007
  • N. Kanazawa
  • Journal of dermatological science
  • 2007
  • Corpus ID: 23818830
C-type lectin receptors are equipped on phagocytes for antigen capturing. Some of them seem to have a major role in cellular… Expand
Highly Cited
2006
Highly Cited
2006
  • Andrew S. J. Marshall, Janet A. Willment, +6 authors Gordon D. Brown
  • European journal of immunology
  • 2006
  • Corpus ID: 12837862
C‐type lectins are the most diverse and prevalent lectin family in immunity. Particular interest has recently been attracted by… Expand
2006
2006
Phosphonopyruvate (P-pyr) hydrolase (PPH), a member of the phosphoenolpyruvate (PEP) mutase/isocitrate lyase (PEPM/ICL… Expand
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Highly Cited
2004
Highly Cited
2004
Inhibitory and activatory C-type lectin-like receptors play an important role in immunity through the regulation of leukocytes… Expand
Highly Cited
2000
Highly Cited
2000
The Saccharomyces cerevisiae ICL1 gene encodes isocitrate lyase, an essential enzyme for growth on ethanol and acetate. Previous… Expand
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Highly Cited
1975
Highly Cited
1975
A rapid focus-induction assay has been developed for certain replicating (r+) but nontransforming (t−) mammalian type C viruses… Expand