2-hydroxytacrine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2012
0119942012

Papers overview

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2012
2012
The current study aims to investigate the pharmacokinetics and brain disposition of tacrine and its three major bioactive… (More)
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2004
2004
Tacrine, a cholinesterase inhibitor, was approved for the treatment of Alzheimer's disease. Oxidative metabolism of tacrine… (More)
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1999
1999
Objective: In vitro studies have shown that tacrine is metabolized by cytochrome P4501A2 (CYP1A2). One of the monohydroxy… (More)
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1998
1998
A new method for the simultaneous quantitation of tacrine and the three metabolites, 1-hydroxytacrine (velnacrine, maleate), 2… (More)
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1996
1996
Plasma tacrine, 1-hydroxytacrine, 2-hydroxytacrine, and 4-hydroxytacrine concentrations were measured in 12 healthy elderly… (More)
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1994
1994
An analytical method was developed for the simultaneous reversed-phase (cyano) high-performance liquid chromatographic… (More)
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