2-hydroxytacrine
National Institutes of Health
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Tacrine, a cholinesterase inhibitor, was approved for the treatment of Alzheimer's disease. Oxidative metabolism of tacrine…
AbstractObjective: In vitro studies have shown that tacrine is metabolized by cytochrome P4501A2 (CYP1A2). One of the monohydroxy…
An analytical method was developed for the simultaneous reversed-phase (cyano) high-performance liquid chromatographic…