Skip to search formSkip to main contentSkip to account menu

2-aminosuberic acid

Known as: 2-aminosuberate, alpha-2-aminooctanedioate, Octanedioic acid, 2-amino-, (R)- 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Amino Acids, Dicarboxylic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Synthesis of 2-aminosuberic acid derivatives as components of some histone deacetylase inhibiting cyclic tetrapeptides
A new synthesis of the important amino acid 2-aminosuberic acid from aspartic acid is reported. The methodology involves the… 
Highly Cited
2012
Highly Cited
2012
Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors
Histone deacetylase (HDAC) inhibitors are being intensively pursued as potential new drugs for a range of diseases, including… 
Highly Cited
2010
Highly Cited
2010
Ex Vivo Activity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates of Plasmodium falciparum and P. vivax
ABSTRACT Histone acetylation plays an important role in regulating gene transcription and silencing in Plasmodium falciparum… 
Review
2009
Review
2009
Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and beta-hemoglobinopathies.
After the approval of suberoylanilide hydroxamic acid (SAHA, vorinostat, Zolinza) for the treatment of cutaneous T cell lymphoma… 
Highly Cited
2008
Highly Cited
2008
Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues
ABSTRACT The malaria parasite Plasmodium falciparum has at least five putative histone deacetylase (HDAC) enzymes, which have… 
Highly Cited
2006
Highly Cited
2006
Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.
Chemotherapy in the last century was characterized by cytotoxic drugs that did not discriminate between cancerous and normal cell… 
1979
1979
An evaluation of D-alpha-aminoadipate and D-(and DL-)alpha-aminosuberate as selective antagonists of excitatory amino acids in the substantia nigra and mesencephalic reticular formation of the rat.
1974
1974
A neurohypophyseal hormone analog with selective oxytocin-like activities and resistance to enzymatic inactivation: an approach to the design of peptide drugs.
Stepwise, synthetic alteration of oxytocin, guided by conformational and enzymological considerations, has led to analogs with… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)