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2-aminoethyl diphenylborinate

Known as: 2-APB cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
051020072017

Related topics

Related topics

1 relation

Broader (1)

Boron Compounds

Related mentions per year

Related mentions per year

1961-2018
1960198020002020
2-aminoethyl diphenylborinate
Boron Compounds

Papers overview

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2016
2016
2-Aminoethyl Diphenylborinate Blocks GABAA-Receptor- Mediated Currents in Rat Medial Preoptic Neurons
The effect of 2-aminoethyl diphenylborinate (2-APB), a commonly used drug to modulate inositol-1,4,5-triphosphate (IP3) receptors… (More)
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2015
2015
Simultaneous administration of 2-aminoethyl diphenylborinate and chloroquine reverses chloroquine resistance in malaria parasites.
A nearly complete reversal of chloroquine (CQ) resistance in the CQ-resistant Plasmodium falciparum K-1 strain, with a… (More)
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2014
2014
Protective effect of 2-aminoethyl diphenylborinate on acute ischemia-reperfusion injury in the rat kidney.
BACKGROUND To investigate the protective effect of 2-aminoethyl diphenylborinate (2-APB) against ischemia-reperfusion (I/R… (More)
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2013
2013
Neuroprotection induced by N-acetylcysteine against cytosolic glutathione depletion-induced Ca2+ influx in dorsal root ganglion neurons of mice: role of TRPV1 channels.
Glutathione (GSH) and N-acetylcysteine (NAC) are thiol-containing antioxidants, and also act through a direct reaction with free… (More)
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2010
2010
Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins.
Store-operated calcium entry (SOCE) or calcium release-activated calcium current (I(CRAC)) is a critical pathway to replenish… (More)
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Highly Cited
2010
Highly Cited
2010
Leptin excites proopiomelanocortin neurons via activation of TRPC channels.
Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It… (More)
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2009
2009
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.
Temperature-activated transient receptor potential ion channels (thermoTRPs) are polymodal detectors of various stimuli including… (More)
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2009
2009
Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons.
Kisspeptins, the natural ligands of the G-protein-coupled receptor (GPR)-54, are the most potent stimulators of GnRH-1 secretion… (More)
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Highly Cited
2008
Highly Cited
2008
Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels.
Kisspeptin and its cognate receptor, GPR54, are critical for reproductive development and for the regulation of gonadotropin… (More)
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2007
2007
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell…
The malarial parasite senses the environment to modulate its own cycle. Knowledge of the mechanisms for regulation signaling… (More)
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