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2-acetamidophenanthrene

Known as: 2-acetylaminophenanthrene 
National Institutes of Health

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Broader (1)

Phenanthrenes

Papers overview

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1997
1997
The dual role of 2-acetylaminofluorene in hepatocarcinogenesis: specific targets for initiation and promotion.
1993
1993
The structure and function of the H-ras proto-oncogene are not altered in rat liver tumors initiated by 2-acetylaminofluorene, 2-acetylaminophenanthrene and trans-4-acetylaminostilbene.
1990
1990
Competitive binding affinity of carcinogenic aromatic amines to the rat hepatic aromatic hydrocarbon (Ah) receptor in vitro and potency to induce monooxygenase activity in vivo.
The aromatic amides 2-acetylaminofluorene (2-AAF), its isomer 4-acetylaminofluorene, 2-acetylaminophenanthrene (AAP), trans-4… 
1989
1989
Formation and removal of DNA adducts in target and nontarget tissues of rats administered multiple doses of 2-acetylaminophenanthrene.
2-Acetylaminophenanthrene (2-AAP) is carcinogenic for the mammary gland, small intestine and ear duct in rats, but is not… 
Highly Cited
1988
Highly Cited
1988
32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures.
A 32P-adduct assay for the measurement of low levels (1 adduct per 10(7) nucleotides) of binding of carcinogens to DNA has been… 
1987
1987
Further characterization of the ability of hepatocarcinogens to lower rat liver aryl sulfotransferase activity.
Aryl sulfotransferase (AST) activity in rat liver is thought to be a primary pathway in the bio-activation of various… 
1987
1987
Induction of the aromatic hydrocarbon receptor by trans-4-acetylaminostilbene in rat liver. Comparison with other aromatic amines.
The effect of the aromatic amines 2-acetylaminofluorene (AAF), 2-acetylaminophenanthrene (AAP) and trans-4-acetylaminostilbene… 
Highly Cited
1984
Highly Cited
1984
Formation and removal of DNA adducts in rat liver treated with N-hydroxy derivatives of 2-acetylaminofluorene, 4-acetylaminobiphenyl, and 2-acetylaminophenanthrene.
Formation and removal of hepatic DNA adducts was studied in male Sprague-Dawley rats following single injections of two… 
Highly Cited
1975
Highly Cited
1975
Cytotoxicity of carcinogenic aromatic amides in normal and xeroderma pigmentosum fibroblasts with different DNA repair capabilities.
The effect of exposure to UV irradiation or to the N-acetoxy-ester derivatives of four carcinogenic aromatic amides, 4… 
1975
1975
Adducts between the carcinogen 2-acetamidophenanthrene and adenine and guanine of DNA.
The sulfate and acetate esters of the carcinogen N-hydroxy-2-acetamidophenanthrene attack calf thymus DNA in vitro to yield… 
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