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2-O, 3-O Desulfated Heparin

Known as: O-desulfated Heparin, ODSH 
A heparin derivative in which the 2-O and 3-O sulfate groups of heparin are removed and that lacks anticoagulant activity, with potential anti… 
National Institutes of Health

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NCIt Antineoplastic Agent Terminology

Papers overview

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2018
2018
Early low-anticoagulant desulfated heparin after traumatic brain injury: Reduced brain edema and leukocyte mobilization is associated with improved watermaze learning ability weeks after injury
BACKGROUND Unfractionated heparin administered immediately after traumatic brain injury (TBI) reduces brain leukocyte (LEU… 
2011
2011
Heparin-induced thrombocytopenia : in vitro studies on the interaction of dabigatran , rivaroxaban , and low-sulfated heparin , with platelet factor 4 and anti-PF 4 / heparin antibodies
Heparin is a widely used anticoagulant. Because of its negative charge, it forms complexes with positively charged platelet… 
2007
2007
O‐DESULFATED HEPARIN IMPROVES OUTCOME AFTER RAT CEREBRAL ISCHEMIA/REPERFUSION INJURY
OBJECTIVEInflammatory cascades play a significant role in progressive neurological injury after transient cerebral ischemia. It… 
2002
2002
Effect of N-desulfated heparin on hepatic/renal ischemia reperfusion injury in rats.
AIM To investigate the effect of N-desulfated heparin on hepatic/renal ischemia and reperfusion injury in rats. METHODS Using… 
1989
1989
Chemical N-desulfation of heparin negates its ability to capacitate bovine spermatozoa.
Heparin specifically and saturably binds to bovine spermatozoa and stimulates capacitation as assessed by the ability of… 
1989
1989
In vivo depletion of macrophages by desulfated iota-carrageenan in mice.
Almost 90% of the sulfate groups of iota-carrageenan (CGN) was removed with acid-methanol in an attempt to obtain a product which… 
1986
1986
Action of cholecystokinin analogues on exocrine and endocrine rat pancreas.
In the present study we have examined the abilities of cholecystokinin-(26-33)-amide [CCK-(26-33)-NH2, CCK-8], nonsulfated CCK… 
Highly Cited
1985
Highly Cited
1985
Opiate Antagonistic Function of Cholecystokinin in Analgesia and Energy Balance Systems a
Because several effects of cholecystokinin (CCK) are opposite to those reported for opioids, it seemed likely that CCK may… 
1977
1977
Effect of heparin modification on its activity in enhancing the inhibition of thrombin by antithrombin III.
1977
1977
1H-N.M.R., 13C-N.M.R., and mass spectra of glucosinolates and related compounds.
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