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2,4-dihydroxypyridine

Known as: 4-hydroxy-2-pyridone 
National Institutes of Health

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Broader (1)

Pyridines

Papers overview

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2019
2019
Apiosporamide, A 4-hydroxy-2-pyridone Alkaloid, Induces Apoptosis Via PI3K/Akt Signaling Pathway In Osteosarcoma Cells
Background Osteosarcoma (OS) is a common primary malignant bone tumour in children and young adults. Apiosporamide, a 4-hydroxy-2… 
2018
2018
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Sambutoxin, a representative derivative of 4-hydroxy-2-pyridone, was isolated from Hericium alpestre for the first time in this… 
2018
2018
Correction to Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria
2017
2017
4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis.
2013
2013
Synthesis of 4-Hydroxy-2-pyridone
Ethyl 2-cyano-5-(dimethylamino)-3-methoxypenta-2,4-dienoate(2) was prepared by condensation of N,N-dimethylformamide dimethyl… 
2002
2002
Total synthesis of pyridovericin: studies toward the biomimetic synthesis of pyridomacrolidin.
[reaction: see text] The total synthesis of the novel metabolite pyridovericin 1 is reported. The synthesis of this key… 
1990
1990
4-Heterocyclyloxy-2H-1-benzopyran potassium channel activators.
The reaction of 2,4-dihydroxypyridine (2) with 3,4-epoxy-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile (1) yielded the… 
1983
1983
Sample preparation and estimation of plasma concentration of 3-deazauridine by high-performance liquid chromatography.
A rapid and simple procedure for liquid chromatographic analysis of plasma 3-deazauridine (3-DU), an antineoplastic agent, was… 
1979
1979
Pharmacokinetics and disposition of 3-deazauridine in humans.
3-Deazauridine (3-DAU) pharmacology was studied in 20 patients who received the drug by rapid or continuous infusion. In 8… 
1978
1978
Effects of natural pyrimidines and of certain related compounds on the spontaneous activity of the mouse.
Uracil and perhaps other natural pyrimidines may effect the level of arousal of the mammalian brain since: 1) heterocyclic 6… 
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