2,3-dimethoxy-1,4-naphthoquinone

The endothelium is not considered to be a major energy-requiring organ, but nevertheless endothelial cells have an extensive… Expand

Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red wine's potential to prevent human… Expand

Skeletal muscles produce transient reactive oxygen species (ROS) in response to intense stimulation, disuse atrophy, heat stress… Expand

Exposure of endothelial cells to oxidized low-density lipoprotein (oxLDL) leads to diverse cellular effects, including induction… Expand

During proliferative glomerulonephritis, the early phase of mesangiolysis is linked to increased nitric oxide (NO) production. NO… Expand

Naphthoquinone vitamins (vitamins K) are widely recognized for their role in the gamma-carboxylation of specific glutamyl… Expand

Increasing concentrations (1-100 microM) of the redox cycling quinone, 2,3-dimethoxy-1,4-naphthoquinone (DMNQ), stimulated growth… Expand

Glutathione (GSH) is one of the most important physiological antioxidants involved in detoxification of hydrogen peroxide and… Expand

Quinones are intracellular H2O2 generators that have been used extensively in models of oxidant injury; however, their toxicity… Expand

Quinones are believed to be toxic by a mechanism involving redox cycling and oxidative stress. In this study, we have used 2,3… Expand