Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

2,3-dimethoxy-1,4-naphthoquinone

Known as: DMNQ 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Naphthoquinones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species.
The endothelium is not considered to be a major energy-requiring organ, but nevertheless endothelial cells have an extensive… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Highly Cited
2009
Highly Cited
2009
Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4).
  • G. Spanier, H. Xu, +5 authors H. Li
  • Journal of physiology and pharmacology : an…
  • 2009
    • Corpus ID: 9876767
Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red wine's potential to prevent human… Expand
  • figure 1
  • figure 2
  • figure 5
  • figure 3
  • figure 6
Highly Cited
2002
Highly Cited
2002
Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress.
Exposure of endothelial cells to oxidized low-density lipoprotein (oxLDL) leads to diverse cellular effects, including induction… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 3
Highly Cited
1997
Highly Cited
1997
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis.
During proliferative glomerulonephritis, the early phase of mesangiolysis is linked to increased nitric oxide (NO) production. NO… Expand
Highly Cited
1995
Highly Cited
1995
Interleukin 6 production by lipopolysaccharide-stimulated human fibroblasts is potently inhibited by naphthoquinone (vitamin K) compounds.
Naphthoquinone vitamins (vitamins K) are widely recognized for their role in the gamma-carboxylation of specific glutamyl… Expand
Highly Cited
1994
Highly Cited
1994
Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.
Increasing concentrations (1-100 microM) of the redox cycling quinone, 2,3-dimethoxy-1,4-naphthoquinone (DMNQ), stimulated growth… Expand
Highly Cited
1994
Highly Cited
1994
Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cells.
Glutathione (GSH) is one of the most important physiological antioxidants involved in detoxification of hydrogen peroxide and… Expand
Highly Cited
1993
Highly Cited
1993
Extracellular glutathione and gamma-glutamyl transpeptidase prevent H2O2-induced injury by 2,3-dimethoxy-1,4-naphthoquinone.
Quinones are intracellular H2O2 generators that have been used extensively in models of oxidant injury; however, their toxicity… Expand
Highly Cited
1988
Highly Cited
1988
Redox cycling and sulphydryl arylation; their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes.
Quinones are believed to be toxic by a mechanism involving redox cycling and oxidative stress. In this study, we have used 2,3… Expand
Highly Cited
1986
Highly Cited
1986
The role of oxidative processes in the cytotoxicity of substituted 1,4-naphthoquinones in isolated hepatocytes.
In order to clarify the role of oxidative processes in cytotoxicity we have studied the metabolism and toxicity of 2-methyl-1,4… Expand
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE