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2'-fluoro-2'-deoxyadenosine

Known as: 2'-deoxy-2'-fluoroadenosine, 5'-FDA 
 
National Institutes of Health

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2 relations
2'-deoxy-2-fluoroadenosine

Broader (1)

Deoxyadenosines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides.
Thermostable nucleoside phosphorylases are attractive biocatalysts for the synthesis of modified nucleosides. Hence we report on… Expand
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2005
2005
Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY.
The oxidation product of 2'-deoxyguanosine, 7,8-dihydro-8-oxo-2'-deoxyguanosine (OG), produces G:C to T:A transversion mutations… Expand
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2004
2004
A residue in MutY important for catalysis identified by photocross-linking and mass spectrometry.
MutY is an adenine glycosylase in the base excision repair (BER) superfamily that is involved in the repair of 7,8-dihydro-8-oxo… Expand
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2003
2003
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state…
The oxidized guanine lesion 7,8-dihydro-8-oxo-2'-deoxyguanosine (OG) is highly mutagenic, resulting in G:C to T:A transversion… Expand
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2003
2003
Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.
We explored the specificity and nature of the nucleotide-binding pocket of the CCA-adding enzyme (tRNA nucleotidyltransferase) by… Expand
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1995
1995
Potent inhibitors of human inosine monophosphate dehydrogenase type II. Fluorine-substituted analogues of thiazole-4-carboxamide adenine dinucleotide.
Three analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) (1-3) containing a fluorine atom at the C2' of the adenine… Expand
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Highly Cited
1993
Highly Cited
1993
Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets.
"Uniformly" modified phosphodiester or phosphorothioate oligonucleotides incorporating 2'-deoxy-2'-fluoroadenosine, -guanosine… Expand
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1991
1991
Study of a hammerhead ribozyme containing 2'-modified adenosine residues.
The improved synthesis of 2'-fluoro-2'-deoxyadenosine (2'-FA) starting from adenosine is described. This compound was converted… Expand
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1984
1984
Recognition by restriction endonuclease EcoRI of deoxyoctanucleotides containing modified sugar moieties.
The deoxyribooctanucleotide d(G-G-A-A-T-T-C-C), containing the recognition sequence for EcoRI, d(G-A-A-T-T-C), and analogs… Expand
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1981
1981
Synthesis and characterization of the dinucleoside monophosphates containing 2'-fluoro-2'-deoxyadenosine.
Three dinucleoside monophosphates containing 2'-fluor-2'-deoxyadenosine (dAfl), dAfl-dAfl, dAfl-A, and A-dAfl, were synthesized… Expand
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