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17-hydroxypregnenolone

Known as: 17-OH-Pregnenolone, Hydroxypregnenolone, 17a-Pregnenolone 
An endogenous steroid hormone synthesized by the hydroxylation of pregnenolone, which can act either as a neuroactive steroid or as a prohormone for… 
National Institutes of Health

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12 relations

Narrower (4)

16 alpha-hydroxypregnenolone 7-(O-carboxymethyl)oxime17-hydroxypregnenolone sulfate19-hydroxypregnenolone 3-acetate21-hydroxypregnenolone
17-Hydroxypregnenolone:MRat:24H:Urine:QnIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Prolactin increases the synthesis of 7alpha-hydroxypregnenolone, a key factor for induction of locomotor activity, in breeding male Newts.
We recently found that the Japanese red-bellied newt, Cynops pyrrhogaster, actively produces 7alpha-hydroxypregnenolone, a… 
2004
2004
Glucose action and adrenocortical biosynthesis in women with polycystic ovary syndrome.
2003
2003
Chemical synthesis of 7- and 8-dehydro derivatives of pregnane-3,17α,20-triols, potential steroid metabolites in Smith–Lemli–Opitz syndrome
Highly Cited
1993
Highly Cited
1993
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
Progesterone and pregnenolone are metabolized to 17 alpha-hydroxysteroids by a cytochrome P450-dependent 17 alpha-hydroxylase… 
1983
1983
The in vitro synthesis of final maturational steroids by ovaries of brook trout (Salvelinus fontinalis) and yellow perch (Perca flavescens).
Highly Cited
1981
Highly Cited
1981
Assessment of eleven adrenal steroids from a single serum sample by combination of automatic high-performance liquid chromatography and radioimmunoassay (HPLC-RIA)*.
Highly Cited
1977
Highly Cited
1977
Steroidogenesis in human follicles approaching ovulation as judged from assays of follicular fluid.
Human chorionic gonadotrophin (HCG) was given to patients at mid-cycle before the endogenous LH surge. Graafian follicles were… 
Highly Cited
1973
Highly Cited
1973
Radioimmunoassay of plasma pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone under various physiological conditions.
Abstract Combining a simple chromatographic system on celite microcolumns with specific antisera as binding reagents… 
Highly Cited
1970
Highly Cited
1970
Steroids of invertebrates. V. The in vitro biosynthesis of steroids by the male-phase ovotestis of the slug (Ariolimax californicus).
Highly Cited
1969
Highly Cited
1969
Steroid metabolism in the human foeto-placental unit.
The concept of a fetoplacental unit as a steroid-synthesizing unit was elaborated by perfusing the previable fetus and placenta… 
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