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C2orf40 gene

Known as: C2orf40, ESOPHAGEAL CANCER-RELATED GENE 4, ECRG4 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Serum exosomes contain ECRG4 mRNA that suppresses tumor growth via inhibition of genes involved in inflammation, cell proliferation, and angiogenesis
Esophageal cancer related gene-4 (Ecrg4) has been shown to be a tumor suppressor in many organs. Exosomes are naturally secreted… 
2018
2018
Identification of Differentially Expressed Genes Induced by Aberrant Methylation in Oral Squamous Cell Carcinomas Using Integrated Bioinformatic Analysis
Oral squamous cell carcinoma (OSCC) is a malignant disease. Methylation plays a key role in the etiology and pathogenesis of OSCC… 
2018
2018
UBE2C is involved in the functions of ECRG4 on esophageal squamous cell carcinoma.
2016
2016
ECRG4 as a novel tumor suppressor gene inhibits colorectal cancer cell growth in vitro and in vivo
Esophageal cancer related gene 4 (ECRG4) as a tumor suppressor gene inhibits the growth and development of various tumors… 
Review
2015
Review
2015
ECRG4 Expression in Normal Rat Tissues: Expression Study and Literature Review
The Esophageal Cancer Related Gene 4 (ECRG4) is a highly conserved tumour suppressor gene encoding various peptides (augurin, C… 
2015
2015
A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms
Human esophageal cancer-related gene 4 (ECRG4) is a potential tumor suppressor gene isolated from human esophageal epithelial… 
2014
2014
Molecular profiling of chordoma
The molecular basis of chordoma is still poorly understood, particularly with respect to differentially expressed genes involved… 
Highly Cited
2011
Highly Cited
2011
Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury
BackgroundThe content and composition of cerebrospinal fluid (CSF) is determined in large part by the choroid plexus (CP) and… 
Highly Cited
2010
Highly Cited
2010
Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion
BackgroundECRG4 has been shown to be a candidate tumor suppressor in several tumors, but its role in glioma remains poorly… 
Highly Cited
2009
Highly Cited
2009
ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
BackgroundCancer cells display widespread changes in DNA methylation that may lead to genetic instability by global… 
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