141W94
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
The strategy currently applied to the treatment of HIV infection is to reduce the viral burden (HIV RNA) to undetectable levels…
ABSTRACT A phase I, open-label, dose-escalating trial was conducted to evaluate the safety, tolerability, and pharmacokinetics of…
Two studies, concerning the synthesis of original nucleoside analogs regarded as an application of heterochemistry on…
ABSTRACT The therapeutic success of an antiretroviral salvage regimen containing protease inhibitors (PI) is limited by PI…
ABSTRACT The use of combinations of anti-human immunodeficiency virus (anti-HIV) agents targeted to different molecular targets…
There are a number of new developments in the fight against the HIV epidemic. New drugs are being developed, results are being…
A new trial of the experimental protease inhibitor 141W94 (VX-478) is being conducted with protease inhibitor-naive patients…
A phase II multicenter trial is underway to test the effectiveness of three new antiretrovirals in patients who are failing…
Compound 141W94 (Vertex VX478) (3S)-tetrahydro-3-furyl N-[((S,2R)-3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl- 2…