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14-methoxymetopon

Known as: Morphinan-6-one, 4,5-epoxy-3-hydroxy-14-methoxy-5,17-dimethyl-, (5alpha)- 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Morphine Derivatives Including Cocaine

Papers overview

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2014
2014
Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity.
Here we have studied regulatory changes of µ-opioid receptors accompanying in vivo 14-methoxymetopon treatments of rats… 
2007
2007
14-methoxymetopon, a highly potent μ opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats
RationaleIncreased opioidergic activity is thought to increase the propensity to consume ethanol. However, the dose monotonicity… 
2006
2006
Separation of Binding Affinity and Intrinsic Activity of the Potent μ-Opioid 14-Methoxymetopon
Receptor binding studies of 5,14-O-dimethyloxymorphone (14-methoxymetopon) in brain membranes have established its high affinity… 
2006
2006
Peripherally mediated antinociception of the mu-opioid receptor agonist 2-[(4,5alpha-epoxy-3-hydroxy-14beta-methoxy-17-methylmorphinan-6beta-yl)amino]acetic acid (HS-731) after subcutaneous and oral…
Opioids induce analgesia by activating opioid receptors not only within the central nervous system but also on peripheral sensory… 
2000
2000
Signal transduction efficacy of the highly potent mu opioid agonist 14-methoxymetopon.
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