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14-methoxymetopon

Known as: Morphinan-6-one, 4,5-epoxy-3-hydroxy-14-methoxy-5,17-dimethyl-, (5alpha)- 
 
National Institutes of Health

Papers overview

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2010
2010
Opioids are the most effective analgesics for pain management, and efficient pain control is a therapeutic priority. Herein, we… Expand
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2007
2007
RationaleIncreased opioidergic activity is thought to increase the propensity to consume ethanol. However, the dose monotonicity… Expand
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2006
2006
Previous studies showed that opioid drugs-oxycodone-6-oxime and 14-methoxy-5-methyl-dihydromorphinone (14-methoxymetopon… Expand
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2005
2005
Novel 14-alkoxy-substituted (e.g. allyloxy, benzyloxy, naphthylmethoxy) morphinan-6-one derivatives were synthesized and… Expand
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2003
2003
The highly potent micro -opioid receptor agonist 14-methoxymetopon (4,5alpha-epoxy-3-hydroxy-14beta-methoxy-5beta,17… Expand
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2003
2003
14-Methoxymetopon is a potent opioid analgesic. When given systemically, it is approximately 500-fold more active than morphine… Expand
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2002
2002
We have studied the effects of 14-methoxymetopon (HS 198), a potent opioid agonist, on the responses to the tail electric… Expand
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2000
2000
In search of a truly high-efficacy (i.e., tau > 100) mu opioid analgesic, we determined the efficacy (tau) and apparent in vivo… Expand
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2000
2000
UNLABELLED Opioids of the mu-receptor type depress respiration and induce addiction. At 10-min intervals 14-methoxymetopon (HS… Expand
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1993
1993
The newly synthesized 14-alkoxymetopon derivatives, 14-methoxymetopon, 14-ethoxymetopon, 14-methoxy-5-methyl-morphinone, exhibit… Expand
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