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Much work has been done to identify susceptibility genes in schizophrenia and bipolar disorder. Several well established linkages… Expand Human neocentromeres are fully functional centromeres that provide mitotic stability to rearranged chromosomes that have… Expand Bipolar disorder (BP) is a severe and common psychiatric disorder characterized by extreme mood swings. Family, twin and adoption… Expand Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses, including cell growth, differentiation… Expand Bipolar disorder is a severe mental illness characterized by mood swings of elation and depression. Family, twin, and adoption… Expand Schizophrenia is a common disorder characterized by psychotic symptoms; diagnostic criteria have been established. Family, twin… Expand Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular… Expand Holoprosencephaly (HPE) is the most common structural anomaly of the human brain and is one of the anomalies seen in patients… Expand Patients with interstitial deletions of the long arm of chromosome 13 may have widely varying phenotypes. From cytogenetic… Expand Several steps in the clinical evolution of human neoplasia are associated with a variety of recurrent chromosomal defects that… Expand