1-methyluric acid

 
National Institutes of Health

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1-methylurate

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Uric Acid
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
In vitro antioxidant activity of coffee compounds and their metabolites.
In this paper we report the antioxidant activity of different compounds which are present in coffee or are produced as a result… (More)
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2005
2005
Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.
OBJECTIVES To set up a novel simple, sensitive, and reliable ion-pairing HPLC method for the synchronous separation of several… (More)
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2005
2005
Phenotype-genotype analysis of CYP1A2 in Japanese patients receiving oral theophylline therapy
To clarify the association between the cytochrome P450 (CYP) 1A2 genotype with the CYP1A2 phenotype and to search for the CYP1A2… (More)
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2005
2005
Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type…
OBJECTIVES Pharmacokinetics of theophylline was investigated in Cyp1(+/+) wild-type mice, Cyp1a1(-/-) and Cyp1a2(-/-) knockout… (More)
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Highly Cited
2000
Highly Cited
2000
Antioxidant ability of caffeine and its metabolites based on the study of oxygen radical absorbing capacity and inhibition of LDL peroxidation.
  • Chul Heon Lee
  • Clinica chimica acta; international journal of…
  • 2000
Although caffeine has been suggested as an antioxidant at millimolar concentrations, little information is available about the… (More)
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Review
1996
Review
1996
The use of caffeine as a metabolic probe for human drug metabolizing enzymes.
1. Caffeine (CA) is metabolized extensively and at least 17 metabolites arising from primary and secondary biotransformation… (More)
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1986
1986
The psychopharmacological and electrophysiological effects of single doses of caffeine in healthy human subjects.
The effects of single doses of anhydrous caffeine (250 mg and 500 mg) and placebo on physiological, psychological measures and… (More)
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1985
1985
Comparative metabolic disposition of [1-Me14C]caffeine in rats, mice, and Chinese hamsters.
The metabolic disposition of [1-Me14C]caffeine has been studied and compared in three male rodent species: the rat, the mouse… (More)
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1982
1982
Human metabolism of [1-methyl-14C]- and [2-14C]caffeine after oral administration.
Radiolabeled caffeine was administered orally at 5 mg/kg to adult, male volunteers. Blood, saliva, expired CO2, urine, and feces… (More)
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1979
1979
Influence of methylxanthine-containing foods on theophylline metabolism and kinetics.
The metabolism and kinetics of 14C-labeled theophylline have been studied after intravenous doses of 100 mg to healthy subjects… (More)
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