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1-methyluric acid

National Institutes of Health

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1-methylurate

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Uric Acid
analogs & derivatives

Papers overview

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2006
2006
Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2–mediated theophylline metabolism by fluvoxamine
Review
2005
Review
2005
Improved HPLC assay for measuring serum vitamin C with 1-methyluric acid used as an electrochemically active internal standard.
The National Health and Nutrition Examination Survey (NHANES) laboratory at CDC has used a modification of methods (1)(2) with… 
2001
2001
Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of…
1999
1999
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
To choose a sensitive protocol to discriminate populations exposed and not exposed to inducers, five urinary metabolite ratios… 
1996
1996
Determination of theophylline and its metabolites in human urine and plasma by high-performance liquid chromatography.
Highly Cited
1996
Highly Cited
1996
Determination of urinary metabolites of caffeine for the assessment of cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activity in humans.
Caffeine metabolism via the 3-demethylation pathway is sequentially catalyzed by cytochrome P4501A2 (CYP1A2), xanthine oxidase… 
Highly Cited
1993
Highly Cited
1993
Alterations in theophylline metabolism during the first year of life
Maturational changes in theophylline disposition were evaluated in 52 infants (gestational age, 24 to 40 weeks; postnatal age, 2… 
1981
1981
Depression of theophylline metabolism and elimination by troleandomycin and erythromycin.
Highly Cited
1979
Highly Cited
1979
Effects of phenobarbital and 3-methylcholanthrene pretreatment on the plasma half-life and urinary excretion profile of theophylline and its metabolites in rats.
1972
1972
Urinary excretion of caffeine and its metabolites in the mouse.
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