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1-hydroxy-7-azabenzotriazole

Known as: 7-aza-1-hydroxybenzotriazole 
National Institutes of Health

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2 relations

Broader (2)

Aza CompoundsTriazoles

Papers overview

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2012
2012
Synthesis of 5'-terminal capped oligonucleotides using O-N phosphoryl migration of phosphoramidite derivatives.
Trivalent phosphoramidite derivatives could be readily converted by reacting with 1-hydroxy-7-azabenzotriazole to phosphotriester… 
2009
2009
Total synthesis of cyclosporin O: exploring the utility of Bsmoc-NMe-amino acid fluorides and KOAt.
Cyclosporin O (CyO), an immunosuppressent cyclic undecapeptide, was synthesized by convergent approach employing Bsmoc-Nmethyl… 
2009
2009
Synthesis and application of N‐[1‐(4‐(4‐fluorophenyl)‐2,6‐dioxocyclohexylidene)ethyl] (Fde)‐protected amino acids for optimization of solid‐phase peptide synthesis using gel‐phase 19F NMR…
N‐[1‐(4‐(4‐fluorophenyl)‐2,6‐dioxocyclohexylidene)ethyl] (Fde) protected amino acids have been prepared and applied in solid… 
2006
2006
Delay of coupling caused by excess additives
Use of excess quantity of additives such as 1‐hydroxybenzotriazole, 1‐hydroxy‐7‐azabenzotriazole, or 3,4‐dihydro‐3‐hydroxy‐4‐oxo… 
2005
2005
Three-dimensional arrangement of sugar residues along helical polypeptide backbone. 2. Synthesis of periodic N-glycosylated peptides by polymerization of tripeptide active esters containing alpha…
New type of N-glycosylated peptides having periodic sequence of -[X-Gln(beta-D-GlcNAc)-Aib]- [X = L-Glu(OMe), L-Lys(Ac), L-Ala… 
2004
2004
Efficient solid-phase synthesis of a large peptide by a single coupling protocol with a single HPLC purification step
Peptide chain assembly is now routinely performed by the use of automated synthesizers, although purification and… 
1999
1999
First total synthesis of N-4909 and its diastereomer; a stimulant of apolipoprotein E secretion in human hepatoma Hep G2 cells.
Both (R)- and (S)-3-hydroxy-13-methyltetradecanoic acids were prepared via a lipase-catalyzed enantioselective acylation. The… 
1999
1999
Synthesis and reactivity of various isomers of 7-aza-1-hydroxybenzotriazole (HOAt): Implications for a mechanistic understanding of their use as peptide coupling additives
1998
1998
SYNTHESIS OF PEPTIDES EMPLOYING FMOC-AMINO ACID CHLORIDES AND COMMERCIAL ZINC DUST
1997
1997
Efficient solid-phase synthesis of a large peptide by a single coupling protocol with a single HPLC purification step
Peptide chain assembly is now routinely performed by the use of automated synthesizers, although purification and… 
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