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1-hydroxy-7-azabenzotriazole

Known as: 7-aza-1-hydroxybenzotriazole 
National Institutes of Health

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Related topics

2 relations

Broader (2)

Aza CompoundsTriazoles

Papers overview

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Highly Cited
2016
Highly Cited
2016
Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries.
DNA-encoded combinatorial libraries are increasingly being used as tools for the discovery of small organic binding molecules to… 
2010
2010
Sulfonate esters of 1-hydroxypyridin-2(1H)-one and ethyl 2-cyano-2-(hydroxyimino)acetate (oxyma) as effective peptide coupling reagents to replace 1-hydroxybenzotriazole and 1-hydroxy-7…
A new family of sulfonate ester-type coupling reagents is described which differs in its leaving group. The sulfonate ester… 
2009
2009
Reactions of monoaryl-substituted methylenecyclobutanes and methylenecyclopropanes with 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and 1-hydroxysuccinimide (HOSu).
  • M. Jiang, M. Shi
  • The Journal of organic chemistry
  • 2009
  • Corpus ID: 39585696
Monoaryl-substituted methylenecyclobutanes (MCBs) and methylenecyclopropanes (MCPs) react with 1-hydroxybenzotriazole (HOBt), 1… 
2006
2006
Blind crystal structure prediction of a novel second polymorph of 1-hydroxy-7-azabenzotriazole.
The commercially available peptide coupling reagent 1-hydroxy-7-azabenzotriazole has been shown to crystallize in two polymorphic… 
Highly Cited
2005
Highly Cited
2005
Catalytic ester-amide exchange using group (IV) metal alkoxide-activator complexes.
A process for preparation of amides from unactivated esters and amines has been developed using a catalytic system comprised of… 
2001
2001
The 5,6- and 4,5-benzo derivatives of 1-hydroxy-7-azabenzotriazole.
[structure: see text]. Syntheses of the two benzo derivatives of HOAt are described. Conversion of the two isomers to the… 
1999
1999
Rapid esterification of nucleosides to solid-phase supports for oligonucleotide synthesis using uronium and phosphonium coupling reagents.
Nucleosides can be esterified to solid-phase supports using uronium or phosphonium coupling reagents and a coupling additive… 
1998
1998
SYNTHESIS OF PEPTIDES EMPLOYING FMOC-AMINO ACID CHLORIDES AND COMMERCIAL ZINC DUST
Highly Cited
1997
Highly Cited
1997
Occurrence and Minimization of Cysteine Racemization during Stepwise Solid-Phase Peptide Synthesis(1)(,)(2).
Contrary to the conventional wisdom of the peptide synthesis field, N,S-protected derivatives of cysteine can undergo substantial… 
Highly Cited
1996
Highly Cited
1996
Cyclization of all-L-Pentapeptides by Means of 1-Hydroxy-7-azabenzotriazole-Derived Uronium and Phosphonium Reagents.
Due to their restricted conformational flexibility, cyclic peptides are of great interest in connection with structure-activity… 
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