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1,2-Dimethylhydrazine Dihydrochloride

The chloride salt of a compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may… 
National Institutes of Health

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1,2-Dimethylhydrazine

Papers overview

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2011
2011
Chemoprotective Role of Triphala Against 1,2-Dimethylhydrazine Dihydrochloride Induced Carcinogenic Damage to Mouse Liver
The present study was carried out to investigate the protective role of Triphala (a combination in equal proportions by weight of… 
2000
2000
Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis.
Deregulation of G1 cyclins has been reported in several human and rodent tumors including colon cancer. To investigate the… 
Highly Cited
1984
Highly Cited
1984
Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat.
The incidence, distribution, size, and histopathology of grossly visible intestinal tumors induced by the parenteral… 
Highly Cited
1984
Highly Cited
1984
Morphology and distribution of 1,2-dimethylhydrazine dihydrochloride-induced colon tumors and their relationship to gut-associated lymphoid tissue in the rat.
The histopathology and relationship of sym-dimethylhydrazine dihydrochloride [(DMH) CAS: 306-37-6; 1,2-dimethylhydrazine… 
Highly Cited
1983
Highly Cited
1983
Enhancing effect of vitamin E on murine intestinal tumorigenesis by 1,2-dimethylhydrazine dihydrochloride.
The effect of the antioxidant vitamin E on the tumor-inducing ability of 1,2-dimethylhydrazine dihydrochloride (1,2-DMH) was… 
1981
1981
Effect of antibiotics on incidence of rat intestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride.
The intestinal microflora has been shown to influence the induction of chemical carcinogens responsible for intestinal tumors in… 
1978
1978
Effects of diet on colon carcinogenesis and the immune system in rats treated with 1,2-dimethylhydrazine.
The effects of different types of diets on colon carcinogenesis by 1,2-dimethylhydrazine and on the immune system were studied in… 
Highly Cited
1977
Highly Cited
1977
Influence of gonadal hormones and age on 1,2‐ dimethylhydrazine‐induced colon carcinogenesis
BD‐II and BD‐IX male and female rats received weekly subcutaneous (s.c.) injections of 15 mg/kg 1,2‐dimethylhydrazine… 
Highly Cited
1972
Highly Cited
1972
Tumorigenesis studies with 1,2-dimethylhydrazine dihydrochloride, hydrazine sulfate, and isonicotinic acid in golden hamsters.
Solutions of 0.012% hydrazine sulfate, 0.001% 1,2-dimethylhydrazine dihydrochloride, and 0.5% isonicotinic acid were given… 
Highly Cited
1971
Highly Cited
1971
Blood vessel tumorigenesis by 1,2-dimethylhydrazine dihydrochloride (symmetrical). Gross, light and electron microscopic descriptions. I.
Administration of 0.001% 1,2-dimethylhydrazine dihydrochloride, symmetrical, in the drinking water of 7-week-old randomly bred… 
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