1,2-Dimethylhydrazine

Known as: Hydrazomethane, N,N'-Dimethylhydrazine, 1,2-Dimethylhydrazine [Chemical/Ingredient] 
A compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis… (More)

Topic mentions per year

Topic mentions per year

1967-2017
05019672017

Papers overview

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Highly Cited
2004
Highly Cited
2004
The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of… (More)
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Highly Cited
2001
Highly Cited
2001
An unknown aspect of behavioral state regulation is how the circadian oscillator of the suprachiasmatic nucleus (SCN) regulates… (More)
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Highly Cited
2000
Highly Cited
2000
Leptin has profound effects on food intake, body weight, and neuroendocrine status. The lack of leptin results in hormonal and… (More)
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Highly Cited
1999
Highly Cited
1999
CpG island hypermethylation is known to be associated with gene silencing in cancer. This epigenetic event is generally accepted… (More)
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Highly Cited
1998
Highly Cited
1998
The present study was carried out to examine the chemopreventive effects of carotenoids such as fucoxanthin, lycopene and lutein… (More)
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Highly Cited
1994
Highly Cited
1994
Sphingolipids are in all eukaryotic cells and modulate cell growth, differentiation, and transformation; however, little is known… (More)
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1990
1990
Organosulfur compounds (OSCs) present in garlic and onion oil have been shown to inhibit chemical carcinogenesis. In this study… (More)
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1980
1980
The epidemiologic patterns of large bowel cancer have implicated a diet high in beef as a risk factor. Another study has shown… (More)
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Highly Cited
1977
Highly Cited
1977
Colon cancer can be induced reliably in rodents with 1,2-dimethylhydrazine and azoxymethane (AOM). Our studies deal with the mode… (More)
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Highly Cited
1973
Highly Cited
1973
Thirty-four CF1 mice were given weekly s.c. injections of 20 mg of 1,2-dimethylhydrazine hydrochloride per kg; this treatment… (More)
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