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1,2-Dimethylhydrazine

Known as: Hydrazomethane, N,N'-Dimethylhydrazine, 1,2-Dimethylhydrazine [Chemical/Ingredient] 
A compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis… Expand
National Institutes of Health

Related topics

Related topics

11 relations
1,2-Dimethylhydrazine DihydrochlorideIn Bloodagonistsantagonists & inhibitors
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Broader (3)

Alkylating AgentsCarcinogensMutagens

Narrower (1)

sym-Dimethylhydrazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Mental Health Mobile Phone App Usage, Concerns, and Benefits Among Psychiatric Outpatients: Comparative Survey Study
Background Despite the popularity of mental health apps, it is unknown if they are actually used by those with mental illness… Expand
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Highly Cited
2013
Highly Cited
2013
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.
The mammalian Sir2 ortholog Sirt1 plays an important role in metabolic regulation. However, the role of Sirt1 in the regulation… Expand
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Review
2008
Review
2008
Mechanisms of leptin action and leptin resistance.
The adipose tissue-derived hormone leptin acts via its receptor (LRb) in the brain to regulate energy balance and neuroendocrine… Expand
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Highly Cited
2004
Highly Cited
2004
Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice
The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of… Expand
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Highly Cited
2001
Highly Cited
2001
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
(−)‐Cannabidiol (CBD) is a non‐psychotropic component of Cannabis with possible therapeutic use as an anti‐inflammatory drug… Expand
Highly Cited
2001
Highly Cited
2001
A neural circuit for circadian regulation of arousal
An unknown aspect of behavioral state regulation is how the circadian oscillator of the suprachiasmatic nucleus (SCN) regulates… Expand
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Review
2001
Review
2001
Mouse defensive behaviors: pharmacological and behavioral assays for anxiety and panic
The natural defensive behaviors of laboratory mice have been evaluated in both seminatural and highly structured situations; and… Expand
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Highly Cited
1994
Highly Cited
1994
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice.
Sphingolipids are in all eukaryotic cells and modulate cell growth, differentiation, and transformation; however, little is known… Expand
Highly Cited
1990
Highly Cited
1990
Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds.
Organosulfur compounds (OSCs) present in garlic and onion oil have been shown to inhibit chemical carcinogenesis. In this study… Expand
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Highly Cited
1977
Highly Cited
1977
Investigations into the metabolism and mode of action of the colon carcinogens 1,2‐dimethylhydrazine and azoxymethane
Colon cancer can be induced reliably in rodents with 1,2‐dimethylhydrazine and azoxymethane (AOM). Our studies deal with the mode… Expand
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