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1,2-Dimethylhydrazine

Known as: Hydrazomethane, N,N'-Dimethylhydrazine, 1,2-Dimethylhydrazine [Chemical/Ingredient] 
A compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis… 
National Institutes of Health

Related topics

Related topics

11 relations
1,2-Dimethylhydrazine DihydrochlorideIn Bloodagonistsantagonists & inhibitors

Broader (3)

Alkylating AgentsCarcinogensMutagens

Narrower (1)

sym-Dimethylhydrazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.
Review
2008
Review
2008
Mechanisms of leptin action and leptin resistance.
The adipose tissue-derived hormone leptin acts via its receptor (LRb) in the brain to regulate energy balance and neuroendocrine… 
Highly Cited
2004
Highly Cited
2004
Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice
The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of… 
Highly Cited
2001
Highly Cited
2001
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
(−)‐Cannabidiol (CBD) is a non‐psychotropic component of Cannabis with possible therapeutic use as an anti‐inflammatory drug… 
Highly Cited
2001
Highly Cited
2001
A neural circuit for circadian regulation of arousal
An unknown aspect of behavioral state regulation is how the circadian oscillator of the suprachiasmatic nucleus (SCN) regulates… 
Review
2001
Review
2001
Mouse defensive behaviors: pharmacological and behavioral assays for anxiety and panic
Highly Cited
2000
Highly Cited
2000
Chemical characterization of leptin‐activated neurons in the rat brain
Leptin has profound effects on food intake, body weight, and neuroendocrine status. The lack of leptin results in hormonal and… 
Highly Cited
1994
Highly Cited
1994
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice.
Sphingolipids are in all eukaryotic cells and modulate cell growth, differentiation, and transformation; however, little is known… 
Highly Cited
1990
Highly Cited
1990
Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds.
Organosulfur compounds (OSCs) present in garlic and onion oil have been shown to inhibit chemical carcinogenesis. In this study… 
Highly Cited
1977
Highly Cited
1977
Investigations into the metabolism and mode of action of the colon carcinogens 1,2‐dimethylhydrazine and azoxymethane
Colon cancer can be induced reliably in rodents with 1,2‐dimethylhydrazine and azoxymethane (AOM). Our studies deal with the mode… 
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