Transcription Factor 7 Limits Regulatory T Cell Generation in the Thymus

@article{Barra2015TranscriptionF7,
  title={Transcription Factor 7 Limits Regulatory T Cell Generation in the Thymus},
  author={Melanie M. Barra and David M. Richards and Jenny Hansson and Annette Hofer and Michael Delacher and Jane C. Hettinger and Jeroen Krijgsveld and Markus Feuerer},
  journal={The Journal of Immunology},
  year={2015},
  volume={195},
  pages={3058 - 3070},
  url={https://api.semanticscholar.org/CorpusID:18686986}
}
A regulatory role for TCF7 is proposed in limiting access to the Treg lineage by influencing the required TCR signaling strength of Treg precursors and broadening the repertoire and allowed lower TCR affinities to be recruited into the T Reg lineage.
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