Sensory processing in children with Paediatric Acute-onset Neuropsychiatric Syndrome.

@article{Newby2024SensoryPI,
  title={Sensory processing in children with Paediatric Acute-onset Neuropsychiatric Syndrome.},
  author={Michelle J Newby and Shelly J. Lane and Kirsti Haracz and Janice Tona and Kerrin Palazzi and David Lambkin},
  journal={Australian occupational therapy journal},
  year={2024},
  url={https://api.semanticscholar.org/CorpusID:267300668}
}
This study found that children with PANS experience significant sensory reactivity differences during exacerbation and remission across multiple sensory domains, with a decline in performance during exacerbation.
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Occupational performance patterns in children with paediatric acute‐onset neuropsychiatric syndrome

A marked decline in occupational performance and socialisation during PANS exacerbations, with improvements to typical levels during remission, emphasising the need for targeted interventions to address occupational and social challenges in children with PANS during exacerbations.

19 References

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Children with PANS present with pervasive occupational performance needs during exacerbations, and children and families may benefit from accommodations to maximize function during this turbulent period.

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The results of this survey revealed a surprisingly strong impact of gender and pubertal status on symptom course and chronicity, a high rate of medical comorbidity suggesting generalized immune dysfunction, a profound impact of PANS episodes on functional status, and a role for early resolution of infection through antibiotic treatment in disease course.

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Those with and without acute onset of symptoms had similar symptom presentation, rates of inflammatory conditions, somatic symptoms, and violent thoughts and behaviors.

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Long-term follow-up of these patients using the Swedish national registers will enable a deeper understanding of the course of this patient group and establish whether any of the potential biomarkers identified will be clinically useful.

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The sensory processing factors—namely, Body Awareness, Balance, Touch, and Social Participation—were predictive of the quality of children's engagement in pretend play in the home environment and indicated that, to engage and participate in play, children are involving sensory processing abilities, especially body awareness, balance, and touch.

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