Oxidative stress and antioxidants in cataract development
@article{Lee2023OxidativeSA, title={Oxidative stress and antioxidants in cataract development}, author={Bryanna J Lee and Natalie A Afshari and Peter X Shaw}, journal={Current Opinion in Ophthalmology}, year={2023}, volume={35}, pages={57 - 63}, url={https://api.semanticscholar.org/CorpusID:264490176} }
Oxidative stress is a significant contributor to cataract development, underscoring the importance of antioxidants in diagnosis and treatment, and markers of lipid peroxidation, MDA and 4-HNE, have been shown to reflect disease severity.
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Medicine
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The role of oxidative stress in cataract formation is explored, focusing on critical mechanisms, such as mitochondrial dysfunction, endoplasmic reticulum stress, loss of gap junctions, and various cell death pathways in LECs.
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