Deletions in guaBA and htrA but not clpX or rfaL constitute a live-attenuated vaccine strain of Salmonella Newport to protect against serogroup C2-C3 Salmonella in mice

@article{Fuche2018DeletionsIG,
  title={Deletions in guaBA and htrA but not clpX or rfaL constitute a live-attenuated vaccine strain of Salmonella Newport to protect against serogroup C2-C3 Salmonella in mice},
  author={Fabien J. Fuche and Jennifer A. Jones and Girish Ramachandran and Ellen E. Higginson and Raphael Simon and Sharon M. Tennant},
  journal={Human Vaccines \& Immunotherapeutics},
  year={2018},
  volume={15},
  pages={1427 - 1435},
  url={https://api.semanticscholar.org/CorpusID:49330840}
}
A Salmonella Newport-based live-attenuated vaccine (serogroup C2-C3) elicited strong antibody responses against COPS, flagellin and outer membrane proteins when administered intraperitoneally or orally and significantly reduced the bacterial burden of challenge organisms in the liver and spleen following lethal challenge.

Refinement of a Live Attenuated Salmonella enterica Serovar Newport Vaccine with Improved Safety

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