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Global burden of Shigella infections: implications for vaccine development and implementation of control strategies.
Shigellosis, which continues to have an important global impact, cannot be adequately controlled with the existing prevention and treatment measures, and innovative strategies, including development of vaccines against the most common serotypes, could provide substantial benefits.
Experimental Campylobacter jejuni infection in humans.
Two strains of Campylobacter jejuni ingested by 111 adult volunteers, in doses ranging from 8 x 10(2) to 2x 10(9) organisms, caused diarrheal illnesses that indicates that the pathogenesis of C.Jejuni infection includes tissue inflammation.
Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent.
  • M. Levine
  • Medicine
    The Journal of infectious diseases
  • 1 March 1987
There are four major categories of diarrheagenic Escherichia coli: enterotoxigenic (a major cause of travelers' diarrhea and infant diarrhea in less-developed countries), enteroinvasive (a cause of
Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines
Three strains of enteropathogenic Escherichia coli (EPEC), originally isolated from humans and previously shown to cause diarrhea in human volunteers by unknown mechanisms, and one rabbit EPEC strain
Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin.
It is predicted that EAST1 stimulates the particulate form of guanylate cyclase through the same receptor-binding region as STa and guanylin, a mammalian analog of STa.
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans
Results show for the first time the role of a specific pilus structure in colonization of the human intestine by V. cholerae O1 and exemplify the significance of a genetic regulon in pathogenesis.
Detection of an adherence factor of enteropathogenic Escherichia coli with a DNA probe.
A DNA probe to detect genes conferring localized adherence of enteropathogenic Escherichia coli to Hep-2 cells was evaluated by using E. coli isolates from the stools of Peruvian infants with and without diarrhea and revealed that Hep- 2 adherence was more frequent in some O serogroups of EPEC than in others.