Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
- I. MellinghoffMaria Y Wang P. Mischel
- 10 November 2005
Medicine, Biology
Coexpression of EGFRvIII and PTEN by glioblastoma cells is associated with responsiveness to EGFR kinase inhibitors, and effects of the molecular abnormalities in vitro are identified.
Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain
- Jeffrey C. LeeI. Vivanco I. Mellinghoff
- 1 December 2006
Medicine, Biology
The results suggest extracellular missense mutations as a novel mechanism for oncogenic EGFR activation and may help identify patients who can benefit from EGFR kinase inhibitors for treatment of glioblastoma.
Practicing emergency physicians report performing well on most emergency medicine milestones.
- T. PeckNicole M DuboshC. RosenC. TibblesJ. PopeJ. Fisher
- 1 October 2014
Medicine
Can ED Triage Nurses Reliably Clear the C-Spine in Minor Trauma?
- I. StiellC. Clement J. Perry
- 1 May 2007
Medicine
Emergency Medicine (EM) Faculty Evaluations Do Not Correlate With Performance on a Standardized EM Examination During a Fourth-year Medical Student EM Rotation
- Nicole M DuboshT. PeckEdward UllmanJ. Fisher
- 2014
Medicine