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Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism

Findings provide key insights into molecular functions of BZW2, the potential role of BZW2 in cancer progression, and the utility of interactome data in understanding the function of less-studied proteins.
PubMed (opens in a new tab)

PARP7 inhibition stabilizes STAT1/STAT2 and relieves experimental autoimmune encephalomyelitis in mice

A molecular mechanism via which PARP7 suppresses type I interferon signaling is revealed, offering insights into the immune-modulatory function of PARP7 and suggesting PARP7 inhibition as a potential treatment strategy for multiple sclerosis.
PubMed (opens in a new tab)
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