Glomerular sieving of three neutral polysaccharides, polyethylene oxide and bikunin in rat. Effects of molecular size and conformation
- Daniel AsgeirssonD. VenturoliE. FriesBengt RippeCatarina Rippe
- 1 November 2007
Biology, Medicine
The glomerular sieving coefficients of the mentioned polymers and of the negatively charged and extended protein bikunin are investigated to test the hypothesis that an increase in ‘molecular extension’ will increase the molecule’sglomerular permeability.
Similarity of permeabilities for Ficoll, pullulan, charge‐modified albumin and native albumin across the rat peritoneal membrane
- Daniel AsgeirssonJosefin AxelssonCatarina RippeBengt Rippe
- 1 August 2009
Biology, Medicine
Investigating whether polysaccharides are hyperpermeable also across the continuous capillaries in the rat peritoneum across the glomerular filtration barrier finds none.
Pathways of fluid transport and reabsorption across the peritoneal membrane. Commentary
The study shows that the three-pore model describes the pathways of peritoneal fluid transport well, and in the presence of high solute transport, poor transcellular ultrafiltration was due to loss of the osmotic gradient and an enhanced small- pore reabsorption rate after this gradient dissipated.