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Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood

Evaluating associations of maternal prenatal antidepressant use, anxiety, and depression with cord blood DNA methylation across the genome at birth and test for persistence of associations in early and mid-childhood blood DNA finds the ZNF575 gene is involved in transcriptional regulation but specific functions are largely unknown.
Springer Nature (opens in a new tab)

Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation

Children whose mothers reported higher levels of cumulative maternal stressful life events during pregnancy exhibited differential methylation of cg26579032 in ALKBH3, and differences in DNA methylation at these loci may provide novel insights into potential mechanisms of neurodevelopment in offspring.
Springer Nature (opens in a new tab)

Frequent Bullying Involvement and Brain Morphology in Children

Bullying involvement in young children was associated with differential cortical morphology, and the fusiform gyrus, often involved in facial processing, showed thicker cortex in targets of frequent bullying.
PubMed (opens in a new tab)

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

A meta-analysis to examine the associations between maternal anxiety, measured prospectively during pregnancy, and genome-wide DNAm from umbilical cord blood found no consistent evidence for any robust associations between mother-child anxiety and DNAm in cord blood.
Springer Nature (opens in a new tab)

29.4 HARSH PARENTING AND BRAIN MORPHOLOGY: A LONGITUDINAL POPULATION-BASED STUDY

Publisher (opens in a new tab)

Behavioral and neurostructural correlates of childhood physical violence victimization: Interaction with family functioning

Violence victimization may cause child behavior problems and neurostructural differences associated with them. Healthy family environments may buffer these effects, but neural pathways explaining…
PubMed (opens in a new tab)

Childhood Adversity and Incident Psychotic Experiences in Early Adulthood: Cognitive and Psychopathological Mediators

Abstract Background and Hypothesis Childhood adversity is often described as a potential cause of incident psychotic experiences, but the underlying mechanisms are not well understood. We aimed to…
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Early Parenting and Infant–Parent Attachment: Developmental Origins of Psychotic Experiences

ABSTRACT Introduction The infant–parent relationship is theorized to be related to the origins of psychotic experiences, given the key role of infant–parent attachment and early‐life caregiving in…
PubMed (opens in a new tab)

Harsh Parenting and Child Brain Morphology: A Population-Based Study

A long-term association between harsh parenting and the global brain and amygdala volumes in preadolescents is found, suggesting that adverse rearing environments common in the general population are related to child brain morphology.
SAGE (opens in a new tab)

Observed infant-parent attachment and brain morphology in middle childhood– A population-based study

Novel evidence is provided for a long-term association between the quality of infant-parent attachment and specific brain differences in childhood and this finding was robust to the adjustment for confounders and consistent across hemispheres.
PubMed (opens in a new tab)
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