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xeroderma pigmentosum group A complementing protein

Known as: Xeroderma Pigmentosum Group A Protein [Chemical/Ingredient], Xeroderma Pigmentosum A Protein, XPA Repair Protein 
A ZINC FINGER MOTIF protein that recognizes and interacts with damaged DNA. It is a DNA-binding protein that plays an essential role in NUCLEOTIDE… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

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XPA protein, human

Papers overview

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2014
2014
Effect of point substitutions within the minimal DNA-binding domain of xeroderma pigmentosum group a protein on interaction with DNA intermediates of nucleotide excision repair
Xeroderma pigmentosum factor A (XPA) is one of the key proteins in the nucleotide excision repair (NER) process. The effects of… 
2009
2009
[Genetic susceptibility of single nucleotide polymorphism in MGMT to non-Hodgkin lymphoma].
OBJECTIVE To evaluate the relationship between five single nucleotide polymorphism loci in the MGMT, XPA, XPD and XPG genes and… 
2004
2004
Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH.
Highly Cited
2003
Highly Cited
2003
Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A.
Replication protein A (RPA) is a heterotrimeric single-stranded DNA- (ssDNA) binding protein that can form a complex with the… 
2003
2003
The spatio-temporal organization of DNA-repair: a live cell study
textabstractThe aim of the work outlined in this thesis is to gain more insight into the organization, dynamic properties and… 
Review
2003
Review
2003
Critical DNA damage recognition functions of XPC‐hHR23B and XPA‐RPA in nucleotide excision repair
It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the… 
Highly Cited
2002
Highly Cited
2002
Xeroderma Pigmentosum Complementation Group A Protein (XPA) Modulates RPA-DNA Interactions via Enhanced Complex Stability and Inhibition of Strand Separation Activity*
Replication protein A (RPA) participates in many cellular functions including DNA replication and nucleotide excision repair. A… 
Highly Cited
2000
Highly Cited
2000
A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA.
The xeroderma pigmentosum group A protein (XPA) plays a central role in nucleotide excision repair (NER). To identify proteins… 
Review
1999
Review
1999
Interactions of mammalian proteins with cisplatin-damaged DNA.
Highly Cited
1993
Highly Cited
1993
Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA.
The xeroderma pigmentosum group A complementing protein (XPAC) is involved in an early step of nucleotide excision repair, the… 
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