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xeroderma pigmentosum group A complementing protein

Known as: Xeroderma Pigmentosum Group A Protein [Chemical/Ingredient], Xeroderma Pigmentosum A Protein, XPA Repair Protein 
A ZINC FINGER MOTIF protein that recognizes and interacts with damaged DNA. It is a DNA-binding protein that plays an essential role in NUCLEOTIDE… Expand
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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XPA protein, human

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Highly Cited
2010
Highly Cited
2010
Localization of xeroderma pigmentosum group A protein and replication protein A on damaged DNA in nucleotide excision repair
The interaction of xeroderma pigmentosum group A protein (XPA) and replication protein A (RPA) with damaged DNA in nucleotide… Expand
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2010
2010
Nucleotide Excision Repair by Mutant Xeroderma Pigmentosum Group A (XPA) Proteins with Deficiency in Interaction with RPA*
The xeroderma pigmentosum group A protein (XPA) is a core component of nucleotide excision repair (NER). To coordinate early… Expand
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Highly Cited
2004
Highly Cited
2004
Interaction of selenium compounds with zinc finger proteins involved in DNA repair.
As an essential element, selenium is present in enzymes from several families, including glutathione peroxidases, and is thought… Expand
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Highly Cited
2003
Highly Cited
2003
Xeroderma Pigmentosum Group A Protein Loads as a Separate Factor onto DNA Lesions
ABSTRACT Nucleotide excision repair (NER) is the main DNA repair pathway in mammals for removal of UV-induced lesions. NER… Expand
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2003
2003
Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A.
Replication protein A (RPA) is a heterotrimeric single-stranded DNA- (ssDNA) binding protein that can form a complex with the… Expand
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Review
2002
Review
2002
Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms.
Nickel, cadmium, cobalt, and arsenic compounds are well-known carcinogens to humans and experimental animals. Even though their… Expand
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Highly Cited
2002
Highly Cited
2002
Xeroderma Pigmentosum Complementation Group A Protein (XPA) Modulates RPA-DNA Interactions via Enhanced Complex Stability and Inhibition of Strand Separation Activity*
Replication protein A (RPA) participates in many cellular functions including DNA replication and nucleotide excision repair. A… Expand
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Highly Cited
2002
Highly Cited
2002
Strand-specific binding of RPA and XPA to damaged duplex DNA.
The nucleotide excision repair (NER) pathway is a major pathway used to repair bulky adduct DNA damage. Two proteins, xeroderma… Expand
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Highly Cited
2000
Highly Cited
2000
A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA.
The xeroderma pigmentosum group A protein (XPA) plays a central role in nucleotide excision repair (NER). To identify proteins… Expand
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Highly Cited
1999
Highly Cited
1999
Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours
Metastatic cancer in adults usually has a fatal outcome. In contrast, advanced testicular germ cell tumours are cured in over 80… Expand
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