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voxtalisib
An orally bioavailable small molecule targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K…
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National Institutes of Health
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2018
2018
Title Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging
Kanako Inaba
,
K. Oda
,
+14 authors
T. Fujii
2018
Corpus ID: 262726485
The aim of this study was to clarify the synergistic effects of dual inhibition of the PI3K/mTOR and MAPK pathways in ovarian…
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2018
2018
Pan-PI3K Inhibitor Voxtalisib Active in FL but Less So in CLL, DLBCL
L. Lawrence
2018
Corpus ID: 132138233
In a phase II study, voxtalisib, which targets all four class I PI3Ks, had efficacy in FL but limited clinical effect in MCL…
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