viral terminase complex

Known as: viral terminase complex location 
A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2015
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Papers overview

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2016
2016
Letermovir is a novel anti-HCMV drug in Phase III development that targets the UL56 subunit of the viral terminase complex. In… (More)
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2015
2015
Letermovir is a new drug in Phase 3 clinical development for the prevention of human Cytomegalovirus (HCMV) infections in… (More)
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2015
2015
Packaging of viral genomes inside empty procapsids is driven by a powerful ATP-hydrolyzing motor, formed in many double-stranded… (More)
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Review
2015
Review
2015
Infection with cytomegalovirus is prevalent in immunosuppressed patients. In solid organ transplant and hematopoietic stem cell… (More)
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2013
2013
Cleavage of human cytomegalovirus (HCMV) genomes as well as their packaging into capsids is an enzymatic process mediated by… (More)
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2013
2013
Novel therapies are urgently needed for the management of cytomegalovirus (CMV) disease in high-risk patients. Currently licensed… (More)
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2012
2012
Packaging of viral genomes into preformed procapsids requires the controlled and synchronized activity of an ATPase and a genome… (More)
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2011
2011
Human cytomegalovirus (HCMV) remains the leading viral cause of birth defects and life-threatening disease in transplant… (More)
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2011
2011
We report the first case of cytomegalovirus (CMV) disease treated with AIC246, a novel anti-CMV compound which targets the viral… (More)
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