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viral terminase complex

Known as: viral terminase complex location 
A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
ABSTRACT The prevention and treatment of human cytomegalovirus (HCMV) infections is based on the use of antiviral agents that… Expand
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2016
2016
Letermovir is a novel anti-HCMV drug in Phase III development that targets the UL56 subunit of the viral terminase complex. In… Expand
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2015
2015
Letermovir is a new drug in Phase 3 clinical development for the prevention of human Cytomegalovirus (HCMV) infections in… Expand
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2013
2013
Cleavage of human cytomegalovirus (HCMV) genomes as well as their packaging into capsids is an enzymatic process mediated by… Expand
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2013
2013
Novel therapies are urgently needed for the management of cytomegalovirus (CMV) disease in high-risk patients. Currently licensed… Expand
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Highly Cited
2011
Highly Cited
2011
Human cytomegalovirus (HCMV) remains the leading viral cause of birth defects and life-threatening disease in transplant… Expand
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Highly Cited
2011
Highly Cited
2011
We report the first case of cytomegalovirus (CMV) disease treated with AIC246, a novel anti-CMV compound which targets the viral… Expand
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