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vancomycin biosynthetic process

Known as: vancomycin biosynthesis, vancomycin synthesis, vancomycin anabolism 
The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C… 
National Institutes of Health

Papers overview

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2008
2008
Not so clear on oxygen. Comment on Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis by Widboom et al. (2007), Nature (London), 447, 342-345.
2005
2005
An improved solid-phase methodology for the synthesis of putative hexa- and heptapeptide intermediates in vancomycin biosynthesis.
The biosynthesis of the vancomycin aglycone involves three oxidative phenol coupling reactions, each catalyzed by a discrete… 
2003
2003
Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis.
Gene inactivation studies point to the involvement of OxyC in catalyzing the last oxidative phenol coupling reaction during… 
1998
1998
Total Syntheses of Vancomycin and
Vancomycin, isolated in 1956 from Streptomyces orientalis,[1] is the prototypical member of a large family of antibiotics whose… 
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