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valilactone
Known as:
5-(N-formyl-L-valinyloxy)-2-hexyl-3-hydroxydecanoic lactone
, L-Valine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)hexyl ester, (2S-(2alpha(R*),3beta))-
National Institutes of Health
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Related topics
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1 relation
Broader (1)
Lactones
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Synthesis of novel beta-lactone inhibitors of fatty acid synthase.
Robyn D. Richardson
,
Gil Ma
,
+5 authors
Jeffrey W. Smith
Journal of Medicinal Chemistry
2008
Corpus ID: 5328439
Fatty acid synthase (FAS) is necessary for growth and survival of tumor cells and is a promising drug target for oncology. Here…
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Highly Cited
2006
Highly Cited
2006
Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase.
Gil Ma
,
Manuel Zancanella
,
Yatsandra Oyola
,
Robyn D. Richardson
,
Jeffrey W. Smith
,
D. Romo
Organic Letters
2006
Corpus ID: 35380011
Concise syntheses of orlistat (Xenical), a two-carbon transposed orlistat derivative, and valilactone are described that employ…
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2006
2006
An expeditious enantioselective total synthesis of valilactone.
Yikang Wu
,
Ya‐Ping Sun
Journal of Organic Chemistry
2006
Corpus ID: 42044816
The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic…
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2006
2006
An expeditious enantioselective total synthesis of valilactone
伍贻康
,
孙亚平
2006
Corpus ID: 203913150
The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic…
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1994
1994
Panclicins, novel pancreatic lipase inhibitors. II. Structural elucidation.
K. Yoshinari
,
M. Aoki
,
+5 authors
K. Yokose
Journal of antibiotics (Tokyo. )
1994
Corpus ID: 21504400
Panclicins A-E are novel and potent pancreatic lipase inhibitors produced by Streptomyces sp. NR 0619. Their structures have been…
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Highly Cited
1978
Highly Cited
1978
Valilactone, an inhibitor of esterase, produced by actinomycetes.
M. Kitahara
,
M. Asano
,
+6 authors
H. Nakamura
Journal of antibiotics (Tokyo. )
1978
Corpus ID: 20115930
brane, had important effects on cellular functions1^. These inhibitors included esterastin which inhibited esterase and…
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