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valilactone

Known as: 5-(N-formyl-L-valinyloxy)-2-hexyl-3-hydroxydecanoic lactone, L-Valine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)hexyl ester, (2S-(2alpha(R*),3beta))- 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Lactones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Synthesis of novel beta-lactone inhibitors of fatty acid synthase.
Fatty acid synthase (FAS) is necessary for growth and survival of tumor cells and is a promising drug target for oncology. Here… 
Highly Cited
2006
Highly Cited
2006
Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase.
Concise syntheses of orlistat (Xenical), a two-carbon transposed orlistat derivative, and valilactone are described that employ… 
2006
2006
An expeditious enantioselective total synthesis of valilactone.
The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic… 
2006
2006
An expeditious enantioselective total synthesis of valilactone
The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic… 
1994
1994
Panclicins, novel pancreatic lipase inhibitors. II. Structural elucidation.
Panclicins A-E are novel and potent pancreatic lipase inhibitors produced by Streptomyces sp. NR 0619. Their structures have been… 
Highly Cited
1978
Highly Cited
1978
Valilactone, an inhibitor of esterase, produced by actinomycetes.
brane, had important effects on cellular functions1^. These inhibitors included esterastin which inhibited esterase and… 
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