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vaccine adjuvant

Known as: adjuvants vaccine 
A substance added to a vaccine to improve the immune response so that less vaccine is needed.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells.
2007
2007
Act1-ivating IL-17 inflammation
The signaling adaptor Act1 is now shown in vivo to be essential for interleukin 17–mediated inflammation in the brain during… 
2006
2006
A soluble LAG-3 protein as an immunopotentiator for therapeutic vaccines: Preclinical evaluation of IMP321.
Highly Cited
2004
Highly Cited
2004
Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice.
Review
2004
Review
2004
From toxin to adjuvant: the rational design of a vaccine adjuvant vector, CTA1‐DD/ISCOM
Mucosally active vaccine adjuvants which will prime a full range of local and systemic immune responses against defined antigenic… 
Review
2003
Review
2003
Vaccine adjuvant technology: from mechanistic concepts to practical applications
Distinct types of immune responses are required for efficient elimination of different pathogens. Programming of the desired type… 
Review
2001
Review
2001
Modulation of host responses to blood-stage malaria by interleukin-12: from therapy to adjuvant activity.
Highly Cited
1999
Highly Cited
1999
IL‐12 is a potent neonatal vaccine adjuvant
Neonatal animals show generally poor responsiveness to foreign antigens and are known to display polarized expression of Th2‐like… 
Highly Cited
1999
Highly Cited
1999
Potent activity of soluble B7-IgG fusion proteins in therapy of established tumors and as vaccine adjuvant.
Fusion proteins consisting of the extracellular region of murine B7.1 or B7.2 and the Fc portion of murine IgG2a (B7-IgG) were… 
Highly Cited
1998
Highly Cited
1998
Prevention of Peripheral Tolerance by a Dendritic Cell Growth Factor: Flt3 Ligand as an Adjuvant
Injections of soluble proteins are poorly immunogenic, and often elicit antigen-specific tolerance. The mechanism of this… 
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