uropod retraction

The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell. [GOC:mah, PMID:10704379]
National Institutes of Health

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Topic mentions per year

1994-2015
01219942015

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2015
2015
Neutrophils use chemotaxis to locate invading bacteria. Adenosine triphosphate (ATP) release and autocrine purinergic signaling… (More)
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2015
2015
Megakaryoblastic leukemia 1 (MKL1), also known as MAL or myocardin-related transcription factor A (MRTF-A), is a coactivator of… (More)
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2014
2014
Osteoclasts are multinucleated cells responsible for the resorption of bone and other mineralized tissues during development… (More)
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2013
2013
Filamin-A (FLNa) has been shown to be a key cross-linker of actin filaments in the leading edge of a motile melanoma cell line… (More)
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2009
2009
The membrane-associated adhesion molecule JAM-A is required for neutrophil infiltration in inflammatory or ischemic tissues. JAM… (More)
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2009
2009
Engagement of the costimulatory protein ICOS activates effector/memory T cells in tissue by enhancing TCR-mediated proliferation… (More)
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2008
2008
Polymorphonuclear leukocytes undergo directed movement to sites of infection, a complex process known as chemotaxis. Extension of… (More)
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2002
2002
Neutrophil motility is crucial to effective host defenses against microorganisms. While uropod retraction is a critical step in… (More)
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Highly Cited
2000
Highly Cited
2000
Buffering of intracellular Ca2+ transients in human neutrophils leads to reduced motility due to defective uropod detachment on… (More)
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1994
1994
Employing a newly developed computer-assisted system for visualizing and quantitating cell motility in three dimensions, we have… (More)
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