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uracil catabolic process

Known as: uracil breakdown, uracil catabolism, uracil degradation 
The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not… 
National Institutes of Health

Papers overview

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2011
2011
PYD1 (dihydropyrimidine dehydogenase) initiates the degradation of pyrimidine nucleobases and is located in plastids. In this… 
Highly Cited
2009
Highly Cited
2009
Reductive catabolism of pyrimidine nucleotides occurs via a three-step pathway in which uracil is degraded to β-alanine, CO2 and… 
Review
2008
Review
2008
Objective Approximately 30–40% of grade III–IV toxicity to 5-FU has been associated with partial or profound deficiency in… 
Review
2007
Review
2007
Objective Dihydropyrimidine dehydrogenase (DPD) deficiency accounts for approximately 43% of grade 3–4 toxicity to 5-fluorouracil… 
Highly Cited
1985
Highly Cited
1985
Enzymes of the pyrimidine base catabolism, dihydrouracil dehydrogenase (EC 1.3.1.2), dihydropyrimidinase (EC 3.5.2.2), and beta… 
1985
1985
Kupffer cells, endothelial cells, and hepatocytes were separated by centrifugal elutriation. The rate of uracil formation from [2… 
1985
1985
A selection procedure for uracil catabolism mutant strains involving indicator dye plates was developed. Using this method, a… 
Highly Cited
1984
Highly Cited
1984
We have developed a one-dimensional thin-layer chromatography procedure that resolves the initial substrate uracil and its…