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uracil catabolic process
Known as:
uracil breakdown
, uracil catabolism
, uracil degradation
The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pyrimidine degradation influences germination seedling growth and production of Arabidopsis seeds
S. Cornelius
,
Sandra Witz
,
H. Rolletschek
,
T. Möhlmann
Journal of Experimental Botany
2011
Corpus ID: 43454848
PYD1 (dihydropyrimidine dehydogenase) initiates the degradation of pyrimidine nucleobases and is located in plastids. In this…
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Highly Cited
2009
Highly Cited
2009
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis
R. Zrenner
,
H. Riegler
,
+5 authors
R. D. Slocum
New Phytologist
2009
Corpus ID: 17659222
Reductive catabolism of pyrimidine nucleotides occurs via a three-step pathway in which uracil is degraded to β-alanine, CO2 and…
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Review
2008
Review
2008
Genetic regulation of &bgr;-ureidopropionase and its possible implication in altered uracil catabolism
Holly R Thomas
,
H. Ezzeldin
,
V. Guarcello
,
L. Mattison
,
B. Fridley
,
R. Diasio
Pharmacogenetics & Genomics
2008
Corpus ID: 10940058
Objective Approximately 30–40% of grade III–IV toxicity to 5-FU has been associated with partial or profound deficiency in…
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Review
2007
Review
2007
Genetic regulation of dihydropyrimidinase and its possible implication in altered uracil catabolism
Holly R Thomas
,
H. Ezzeldin
,
V. Guarcello
,
L. Mattison
,
B. Fridley
,
R. Diasio
Pharmacogenetics & Genomics
2007
Corpus ID: 23490646
Objective Dihydropyrimidine dehydrogenase (DPD) deficiency accounts for approximately 43% of grade 3–4 toxicity to 5-fluorouracil…
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Highly Cited
1985
Highly Cited
1985
Enzymes of uracil catabolism in normal and neoplastic human tissues.
F. Naguib
,
M. H. Kouni
,
Sungman Cha
Cancer Research
1985
Corpus ID: 14883134
Enzymes of the pyrimidine base catabolism, dihydrouracil dehydrogenase (EC 1.3.1.2), dihydropyrimidinase (EC 3.5.2.2), and beta…
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1985
1985
Uridine catabolism in Kupffer cells, endothelial cells, and hepatocytes.
A. Holstege
,
H. Leser
,
J. Pausch
,
W. Gerok
European Journal of Biochemistry
1985
Corpus ID: 24764692
Kupffer cells, endothelial cells, and hepatocytes were separated by centrifugal elutriation. The rate of uracil formation from [2…
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1985
1985
A Salmonella typhimurium strain defective in uracil catabolism and beta-alanine synthesis.
T. West
,
T. Traut
,
M. Shanley
,
G. O'donovan
Journal of General Microbiology
1985
Corpus ID: 12975368
A selection procedure for uracil catabolism mutant strains involving indicator dye plates was developed. Using this method, a…
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Highly Cited
1984
Highly Cited
1984
Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay.
T. Traut
,
S. Loechel
Biochemistry
1984
Corpus ID: 21490828
We have developed a one-dimensional thin-layer chromatography procedure that resolves the initial substrate uracil and its…
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Highly Cited
1958
Highly Cited
1958
Enzymes of uracil metabolism in the Ehrlich ascites tumour and mammalian liver.
P. Reichard
,
O. Skold
Biochimica et Biophysica Acta
1958
Corpus ID: 29197617
1957
1957
Reductive degradation of pyrimidines. II. Mechanism of uracil degradation by Clostridium uracilicum.
Campbell Ll
1957
Corpus ID: 222469263
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