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ubiquitin binding

Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic… 
National Institutes of Health

Papers overview

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2015
2015
In vitro detection of NEMO-ubiquitin binding using DELFIA and microscale thermophoresis assays.
Canonical NF-κB signaling in response to various stimuli converges at the level of the IκB kinase (IKK) complex to ultimately… 
2015
2015
Pertussis resurgence in vaccinated populations
Background: Our previous studies have demonstrated that autophagosome-enriched vaccine (named DRibbles: DRiPs-containing blebs… 
2014
2014
The JAMM in the proteasome
Structures of the deubiquitinating enzyme Rpn11 of the proteasomal 19S regulatory particle reveal its role in hydrolyzing the… 
2013
2013
Ubiquitin binding by the p62 UBA domain
Over 30 different mutations in p62 UBA have been identified in patients with Paget's disease of bone (PDB). The mechanisms which… 
2013
2013
Two-sided Ubiquitin Binding of NF-κB Essential Modulator (NEMO) Zinc Finger Unveiled by a Mutation Associated with Anhidrotic Ectodermal Dysplasia with Immunodeficiency Syndrome*
Background: Mutations in the NEMO ZF cause various forms of anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID… 
2013
2013
Probing the affinity, selectivity and inhibition of ubiquitin-ubiquitin binding domain complexes by electrospray ionization mass spectrometry
This thesis describes the development and application of a rapid and sensitive electrospray ionization-mass spectrometry (ESI-MS… 
2013
2013
UBIQUITIN MODULATES TOLLIP\'S PTDINS3P BINDING AND DISSOCIATES THE DIMERIC STATE OF C-TERMINAL CUE DOMAIN
Ubiquitylation is a highly controlled post-translational modification of proteins, in which proteins are conjugated either with… 
2011
2011
Backbone 1H, 13C, and 15N assignments for the tandem ubiquitin binding domains of signal transducing adapter molecule 1
Signal transducing adapter molecule (STAM) forms the endosomal sorting complex required for transport-0 (ESCRT-0) complex with… 
2009
2009
The linker connecting the tandem ubiquitin binding domains of RAP80 is critical for lysine 63-linked polyubiquitin-dependent binding activity.
The tandem ubiquitin-interacting motif (UIM) domain located at the N-terminus of Receptor Associated Protein 80 (RAP80) plays a… 
2002
2002
Cloning and characterization of human ubiquitin binding enzyme 2 cDNA.
OBJECTIVE To clone and identify the gene encoding human ubiquitin binding enzyme 2 and study its expression pattern. METHODS… 
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