type I interferon signaling pathway

Known as: type I interferon-activated signaling pathway, type I interferon-mediated signaling pathway, type I interferon-mediated signalling pathway 
A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
05101519962018

Papers overview

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2017
2017
Viral infection triggers a series of signaling cascades and host innate immune responses, including interferon (IFN) production… (More)
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2016
2016
Hepatitis B virus (HBV) is an important account of infectious hepatitis and interferon (IFN) remains one of the best treatment… (More)
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2015
2015
Lipopolysaccharide (LPS) activates Toll-like receptor 4 (TLR4) through the TIRAP-MyD88 dependent and TRAM-TRIF dependent… (More)
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Highly Cited
2013
Highly Cited
2013
During persistent viral infections, chronic immune activation, negative immune regulator expression, an elevated interferon… (More)
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Highly Cited
2013
Highly Cited
2013
Type I interferons (IFN-I) are critical for antiviral immunity; however, chronic IFN-I signaling is associated with hyperimmune… (More)
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Highly Cited
2010
Highly Cited
2010
Stringent control of the NF-kappaB and type I interferon signaling pathways is critical to effective host immune responses, yet… (More)
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Highly Cited
2010
Highly Cited
2010
Inflammatory cytokines are well-recognized mediators of atherosclerosis. Depending on the pathological context, type I… (More)
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Highly Cited
2009
Highly Cited
2009
M-CSF and GM-CSF are mediators involved in regulating the numbers and function of macrophage lineage populations and have been… (More)
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Highly Cited
2007
Highly Cited
2007
Francisella tularensis is a pathogenic bacterium whose virulence is linked to its ability to replicate within the host cell… (More)
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2004
2004
The epidermal phenotype as observed in psoriatic skin results from inflammation and abnormal proliferation and terminal… (More)
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