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type I interferon signaling pathway

Known as: type I interferon-activated signaling pathway, type I interferon-mediated signaling pathway, type I interferon-mediated signalling pathway 
A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

cellular response to type I interferon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Antiviral immunity backfires: Pathogenic effects of type I interferon signaling in fetal development
Interferon-α/β signaling is pathogenic in a mouse model of congenital Zika virus infection. See related research article by… 
2017
2017
AXL Promotes Zika Virus Infection in Astrocytes by Antagonizing Type I Interferon Signaling Pathway
Zika virus (ZIKV) is known to be associated with neonate microcephaly and Guillain-Barré syndrome in human adults. Despite the… 
2015
2015
The Golgi-Associated Plant Pathogenesis-Related Protein GAPR-1 Enhances Type I Interferon Signaling Pathway in Response to Toll-Like Receptor 4
Lipopolysaccharide (LPS) activates Toll-like receptor 4 (TLR4) through the TIRAP-MyD88 dependent and TRAM-TRIF dependent… 
2015
2015
Glatiramer acetate treatment negatively regulates type I interferon signaling
Objective: Glatiramer acetate (GA; Copaxone), a disease-modifying therapy for multiple sclerosis (MS), promotes development of… 
2013
2013
Type I Interferon Signaling Pathway May Be Involved in Optimal Interleukin-2 Production in CD4+ T Cells
2013
2013
hTERT Extends the Life of Human Fibroblasts without Compromising Type I Interferon Signaling
Primary cells are often used to study viral replication and host-virus interactions as their antiviral pathways have not been… 
2009
2009
Myxoma virus selectively disrupts type I interferon signaling in primary human fibroblasts by blocking the activation of the Janus kinase Tyk2.
2007
2007
Type I Interferon Signaling and B Cells Maintain Hemopoiesis during Pneumocystis Infection of the Lung1
Loss of CD4 T cells is the hallmark of HIV infection. However, type I IFN-producing plasmacytoid dendritic cells may also be lost… 
Review
2004
Review
2004
Mechanisms of type I interferon signaling in normal and malignant cells.
Type I interferons (IFNs) are cytokines that induce multiple biological effects on target cells, including antiviral… 
1997
1997
A Type I Interferon Signaling Factor, ISF21, Encoded on Chromosome 21 Is Distinct from Receptor Components and Their Down-regulation and Is Necessary for Transcriptional Activation of Interferon…
The type I interferons (IFNs) are a family of cytokines, comprising at least 17 subtypes, which exert pleiotropic actions by… 
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