FAQ

type I interferon secretion

Known as: type I IFN secretion 
The regulated release of type I interferon from a cell. [GOC:BHF, GOC:mah, PMID:15546383]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
02420002018

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1 relation

Broader (1)

type I interferon production

Related mentions per year

Related mentions per year

1980-2018
19801990200020102020
type I interferon secretion
type I interferon production

Papers overview

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2015
2015
Hcmv-miR-UL112 attenuates NK cell activity by inhibition type I interferon secretion.
Viral microRNAs (miRNAs) can regulate the host innate immune response. In particular, the human cytomegalovirus (HCMV) miRNA hcmv… (More)
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Highly Cited
2012
Highly Cited
2012
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Toll-like receptor-9 (TLR9) is largely responsible for discriminating self from pathogenic DNA. However, association of host DNA… (More)
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2011
2011
Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes.
It remains unclear whether antibody-dependent-enhancement (ADE) of dengue infection merely augments viral attachment and entry… (More)
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Highly Cited
2009
Highly Cited
2009
A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis.
The effect of interferon-beta in multiple sclerosis is modest and many patients do not respond to treatment. To date, no single… (More)
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2009
2009
Human cytomegalovirus suppresses type I interferon secretion by plasmacytoid dendritic cells through its interleukin 10 homolog.
Type I interferons (IFNs) are innate cytokines with potent antiviral and immunoregulatory activities. It remains unclear how… (More)
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2009
2009
Double-stranded RNA activates type I interferon secretion in glomerular endothelial cells via retinoic acid-inducible gene (RIG)-1.
BACKGROUND The molecular pathomechanisms by which viral infections trigger glomerulonephritis remain elusive. In the glomerulus… (More)
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2007
2007
Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses.
Modified vaccinia virus Ankara (MVA) is a highly attenuated vaccinia virus strain undergoing clinical evaluation as a replication… (More)
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Highly Cited
2006
Highly Cited
2006
Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.
Natural interferon (IFN)-producing cells are the primary cell type responsible for production of type I IFN in response to… (More)
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Highly Cited
2006
Highly Cited
2006
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus.
The innate immune system recognizes viral dsRNA through two distinct pathways; the Toll-like receptor 3 (TLR3) pathway detects… (More)
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Highly Cited
2001
Highly Cited
2001
Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection.
Successful immunologic control of HIV infection is achieved only in rare individuals. Dendritic cells (DCs) are required for… (More)
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