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tubulin deacetylase activity

Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate. [PMID:12024216, PMID:12486003]
National Institutes of Health

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2012
2012
Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and…