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trypanothione reductase activity

Known as: NADPH2:trypanothione oxidoreductase activity, trypanothione-disulfide reductase activity, trypanothione:NADP+ oxidoreductase activity 
Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide. [EC:1.8.1.12]
National Institutes of Health

Papers overview

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2017
2017
Two series of diaryl-tetrahydrofuran and -furan were synthesised and screened for anti-trypanosomal activity against… Expand
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2015
2015
Trypanothione reductase (TR) is a vital enzyme in the trypanothione based redox metabolism of trypanosomatid parasites. It is one… Expand
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2013
2013
Three thioamide-substituted imidazoquinolinone, which possess a heterocyclic center similar to tryptanthrin and are named C1, C2… Expand
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Review
2003
Review
2003
Abstract The bis(glutathionyl)spermidine trypanothione exclusively occurs in parasitic protozoa of the order Kinetoplastida, such… Expand
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1995
1995
Although trypanothione [T(S)2] is the major thiol component in trypanosomatidae, significant amounts of glutathione are present… Expand
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