trimethyllysine dioxygenase activity

Known as: TML-alpha-ketoglutarate dioxygenase activity, trimethyllysine alpha-ketoglutarate dioxygenase activity, TML hydroxylase activity 
Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2… (More)
National Institutes of Health

Papers overview

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2017
2017
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy.
Background Despite a multiplicity of clinical trials testing immune checkpoint inhibitors, the frequency of expression of… (More)
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2017
2017
Analysis and prediction of protein folding energy changes upon mutation by element specific persistent homology
Motivation Site directed mutagenesis is widely used to understand the structure and function of biomolecules. Computational… (More)
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2015
2015
Role of dioxygenase α-DOX2 and SA in basal response and in hexanoic acid-induced resistance of tomato (Solanum lycopersicum) plants against Botrytis cinerea.
Resistance of tomato (Solanum Lycopersicum) to the fungal pathogen Botrytis cinerea requires complex interplay between hormonal… (More)
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2014
2014
Tuning reactivity and mechanism in oxidation reactions by mononuclear nonheme iron(IV)-oxo complexes.
Mononuclear nonheme iron enzymes generate high-valent iron(IV)-oxo intermediates that effect metabolically important oxidative… (More)
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2013
2013
Sucrose promotes strawberry fruit ripening by stimulation of abscisic acid biosynthesis
The interaction of sugar with ABA plays an important role in many aspects of plant growth and development. Although glucose is… (More)
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Highly Cited
2012
Highly Cited
2012
Suppression of 9-cis-epoxycarotenoid dioxygenase, which encodes a key enzyme in abscisic acid biosynthesis, alters fruit texture in transgenic tomato.
Cell wall catabolism during fruit ripening is under complex control and is key for fruit quality and shelf life. To examine the… (More)
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2002
2002
Benzoate 1,2-dioxygenase from Pseudomonas putida: single turnover kinetics and regulation of a two-component Rieske dioxygenase.
The benzoate 1,2-dioxygenase system (BZDOS) from Pseudomonas putida mt-2 catalyzes the NADH-dependent oxidation of benzoate to 1… (More)
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Review
2000
Review
2000
Control of abscisic acid synthesis.
The abscisic acid (ABA) biosynthetic pathway involves the formation of a 9-cis-epoxycarotenoid precursor. Oxidative cleavage then… (More)
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Highly Cited
2000
Highly Cited
2000
Characterization of the 9-cis-epoxycarotenoid dioxygenase gene family and the regulation of abscisic acid biosynthesis in avocado.
Avocado (Persea americana Mill. cv Lula) is a climacteric fruit that exhibits a rise in ethylene as the fruit ripens. This rise… (More)
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1983
1983
Multiple mutations in the T region of the Agrobacterium tumefaciens tumor-inducing plasmid.
Three genetic loci affecting tumor morphology lie within pTiA6NC T-DNA: tms, tmr, and tml. Using deletions and multiple… (More)
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