transcriptional preinitiation complex

Known as: DNA-templated transcriptional preinitiation complex, transcription preinitiation complex, preinitiation complex location 
A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes… (More)
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Review
2010
Review
2010
Inactivation of p53 is critical for the formation of most tumors. Illumination of the key function(s) of p53 protein in… (More)
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Highly Cited
2008
Highly Cited
2008
In vitro, without Mediator, the association of general transcription factors (GTF) and RNA polymerase II (Pol II) in… (More)
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Highly Cited
2007
Highly Cited
2007
We incorporated the non-natural photoreactive amino acid p-benzoyl-L-phenylalanine (Bpa) into the RNA polymerase II (Pol II… (More)
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Highly Cited
2005
Highly Cited
2005
In response to nutrients, energy sufficiency, hormones, and mitogenic agents, S6K1 phosphorylates several targets linked to… (More)
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Highly Cited
2004
Highly Cited
2004
Polycomb group (PcG) proteins maintain the transcriptional silence of target genes through many cycles of cell division. Here, we… (More)
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Highly Cited
2001
Highly Cited
2001
Environmental stress-induced phosphorylation of eIF2alpha inhibits protein translation by reducing the availability of eIF2-GTP… (More)
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Highly Cited
1999
Highly Cited
1999
The basal transcription machinery of Archaea corresponds to the minimal subset of factors required for RNA polymerase II… (More)
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Highly Cited
1998
Highly Cited
1998
Cdc45p, a protein essential for initiation of DNA replication, associates with chromatin after "start" in late G1 and during the… (More)
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Highly Cited
1993
Highly Cited
1993
Eukaryotic activator proteins (activators) stimulate transcription by increasing assembly of the preinitiation complex. We have… (More)
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