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transcriptional preinitiation complex

Known as: DNA-templated transcriptional preinitiation complex, transcription preinitiation complex, preinitiation complex location 
A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The essential and multifunctional TFIIH complex
TFIIH is a 10‐subunit complex that regulates RNA polymerase II (pol II) transcription but also serves other important biological… Expand
Highly Cited
2013
Highly Cited
2013
H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation
Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes… Expand
Highly Cited
2008
Highly Cited
2008
Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the…
Central sensitization, increased sensitivity in spinal cord dorsal horn neurons after injuries, plays an essential role in the… Expand
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Highly Cited
2007
Highly Cited
2007
RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation*
Converging signals from the mammalian target of rapamycin (mTOR) and phosphoinositide 3-kinase (PI3K) pathways are well… Expand
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Highly Cited
2005
Highly Cited
2005
mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events
In response to nutrients, energy sufficiency, hormones, and mitogenic agents, S6K1 phosphorylates several targets linked to… Expand
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Review
2002
Review
2002
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability.
Mammalian stress granules (SGs) are cytoplasmic domains into which mRNAs are sorted dynamically in response to phosphorylation of… Expand
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Highly Cited
1997
Highly Cited
1997
An evaluation of the utility of SSR loci as molecular markers in maize (Zea mays L.): comparisons with data from RFLPS and pedigree
Abstract The utility of 131 simple sequence repeat (SSR) loci to characterize and identify maize inbred lines, validate pedigree… Expand
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Highly Cited
1997
Highly Cited
1997
Steroid receptor coactivator-1 is a histone acetyltransferase
Steroid receptors and coactivator proteins are thought to stimulate gene expression by facilitating the assembly of basal… Expand
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Highly Cited
1995
Highly Cited
1995
Cdk-activating kinase complex is a component of human transcription factor TFIIH
TRANSCRIPTION factor IIH (TFIIH) contains a kinase capable of phosphorylating the carboxy-terminal domain (CTD) of the largest… Expand
Review
1991
Review
1991
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly.
  • R. Roeder
  • Trends in biochemical sciences
  • 1991
    • Corpus ID: 25416756
Individual steps in the assembly of RNA polymerase II and general initiation factors into a preinitiation complex serve as points… Expand
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