FAQ

transcription export complex

Known as: TREX complex, TREX complex location, transcription export complex location 
The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
0246820022018

Papers overview

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2011
2011
The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes.
Different steps in gene expression are intimately linked. In Saccharomyces cerevisiae, the conserved TREX complex couples… (More)
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Highly Cited
2009
Highly Cited
2009
Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.
In metazoans, nuclear export of bulk mRNA is mediated by Tap-p15, a conserved heterodimeric export receptor that cooperates with… (More)
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Highly Cited
2008
Highly Cited
2008
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.
The eukaryotic THO/TREX complex, involved in mRNP biogenesis, plays a key role in the maintenance of genome integrity in yeast… (More)
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Highly Cited
2006
Highly Cited
2006
Human mRNA Export Machinery Recruited to the 5′ End of mRNA
Pre-mRNAs undergo splicing to remove introns, and the spliced mRNA is exported to the cytoplasm for translation. Here we… (More)
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Highly Cited
2006
Highly Cited
2006
Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription.
The mRNA nuclear export receptor Mex67/Mtr2 is recruited to mRNAs through RNA-binding adaptors, including components of the THO… (More)
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Highly Cited
2005
Highly Cited
2005
Recruitment of the human TREX complex to mRNA during splicing.
In yeast, the TREX complex contains the THO transcription elongation complex, which functions in direct cotranscriptional… (More)
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2005
2005
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability.
The conserved eukaryotic THO-TREX complex acts at the interface between transcription and mRNA export and affects transcription… (More)
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2003
2003
Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.
THP1 is a conserved eukaryotic gene whose null mutations confer, in yeast, transcription and genetic instability phenotypes and… (More)
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Highly Cited
2002
Highly Cited
2002
TREX is a conserved complex coupling transcription with messenger RNA export.
The essential yeast proteins Yra1 and Sub2 are messenger RNA export factors that have conserved counterparts in metazoans… (More)
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Highly Cited
2002
Highly Cited
2002
The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.
Yra1p and Sub2p are components of the TREX complex, which couples transcription elongation with nuclear export of mRNAs. Here, we… (More)
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