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transcription export complex 2

Known as: TREX-2 complex location, Sac3-Thp1-Sus1-Cdc31 complex, transcription export complex location 2 
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex… 
National Institutes of Health

Papers overview

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2019
2019
Structure and Function of the TREX-2 Complex.
  • M. Stewart
  • Sub-cellular biochemistry
  • 2019
  • Corpus ID: 210812184
The Three prime repair exonuclease 2 (TREX-2) complex functions as a platform to which many of the components of the nuclear mRNA… 
2018
2018
The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex.
2016
2016
The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region
2016
2016
Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy
The nuclear THO and TREX-2 complexes are implicated in several steps of nuclear mRNP biogenesis, including transcription, 3′ end… 
Highly Cited
2013
Highly Cited
2013
The human TREX-2 complex is stably associated with the nuclear pore basket
Summary In eukaryotes, mRNA export involves many evolutionarily conserved factors that carry the nascent transcript to the… 
Highly Cited
2012
Highly Cited
2012
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export
Export of messenger RNA (mRNA) from the nucleus to the cytoplasm is a critical step in the gene expression pathway of eukaryotic… 
Review
2012
Review
2012
Structural biology of the PCI-protein fold
The PCI fold is based on a stack of α-helices topped with a winged-helix domain and is found in a range of proteins that form… 
2012
2012
Evidence that the Arabidopsis Ubiquitin C-terminal Hydrolases 1 and 2 associate with the 26S proteasome and the TREX-2 complex
The 26S proteasome interacts with a number of different proteins, while the TREX-2 complex is an important component of the mRNA… 
Highly Cited
2010
Highly Cited
2010
Arabidopsis homolog of the yeast TREX-2 mRNA export complex: components and anchoring nucleoporin.
Nuclear pore complexes (NPCs) are vital to nuclear-cytoplasmic communication in eukaryotes. The yeast NPC-associated TREX-2… 
Highly Cited
2009
Highly Cited
2009
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian… 
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