transcription export complex 2

Known as: TREX-2 complex location, Sac3-Thp1-Sus1-Cdc31 complex, transcription export complex location 2 
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex… Expand
National Institutes of Health

Papers overview

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2018
2018
The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex.
The conserved nuclear protein ENY2 (Sus1 in yeast) is involved in coupling transcription and mRNA export in yeast and metazoa, as… Expand
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2016
2016
The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region
UNLABELLED Transcription-export complex 2 (TREX-2 complex) facilitates the localization of actively transcribing genes to the… Expand
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2016
2016
Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy.
The nuclear THO and TREX-2 complexes are implicated in several steps of nuclear mRNP biogenesis, including transcription, 3' end… Expand
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2015
2015
The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression
Nuclear pore complexes (NPCs) influence gene expression besides their established function in nuclear transport. The TREX-2… Expand
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2013
2013
The human TREX-2 complex is stably associated with the nuclear pore basket.
In eukaryotes, mRNA export involves many evolutionarily conserved factors that carry the nascent transcript to the nuclear pore… Expand
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2012
2012
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export
Export of messenger RNA (mRNA) from the nucleus to the cytoplasm is a critical step in the gene expression pathway of eukaryotic… Expand
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Review
2012
Review
2012
Structural biology of the PCI-protein fold
The PCI fold is based on a stack of α-helices topped with a winged-helix domain and is found in a range of proteins that form… Expand
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2012
2012
Evidence that the Arabidopsis Ubiquitin C-terminal Hydrolases 1 and 2 associate with the 26S proteasome and the TREX-2 complex.
The 26S proteasome interacts with a number of different proteins, while the TREX-2 complex is an important component of the mRNA… Expand
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Highly Cited
2009
Highly Cited
2009
Arabidopsis homolog of the yeast TREX-2 mRNA export complex: components and anchoring nucleoporin.
Nuclear pore complexes (NPCs) are vital to nuclear-cytoplasmic communication in eukaryotes. The yeast NPC-associated TREX-2… Expand
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Highly Cited
2009
Highly Cited
2009
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian… Expand
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