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transcainide

Known as: 4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-(2-hydroxycyclohexyl)-4-piperidinecarboxamide 
National Institutes of Health

Papers overview

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2004
2004
SummaryThe antiarrhythmic efficacy of transcainide has been studied in 41 patients. It abolished ventricular arrhythmias in 10… Expand
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1994
1994
This study assessed whether class I antiarrhythmic drugs allosterically inhibit [3H]batrachotoxinin A 20-alpha-benzoate ([3H]BTXB… Expand
1994
1994
Transcainide, a complex derivative of lidocaine, blocks the open state of BTX-activated sodium channels from bovine heart and rat… Expand
1992
1992
The electrophysiology and antiarrhythmic efficacy of R61748, a 4-OH metabolite of R54718 (transcainide), have been studied in… Expand
1991
1991
The mechanism of action of the lidocaine derivative transcainide was examined using [3H]batrachotoxinin 20 alpha-benzoate, which… Expand
1988
1988
  • E. Carmeliet
  • Journal of cardiovascular pharmacology
  • 1988
  • Corpus ID: 22522726
The working mechanism of Na+ channel block by a lidocaine analog, transcainide, was investigated. The Na+ channel block was… Expand
1987
1987
Transcainidse is a new lidocaine analog that has been shown to suppress a range of cardiac arrhythmias in an initial clinical… Expand
1987
1987
Transcainide was selected as an antiarrhythmic drug with potential clinical application. In isolated dog, sheep and rabbit… Expand