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transcainide
Known as:
4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-(2-hydroxycyclohexyl)-4-piperidinecarboxamide
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Lidocaine
Narrower (1)
R 54718
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Evaluation of the efficacy and tolerance of the antiarrhythmic agent transcainide (R 54718)
R. Stroobandt
,
P. Bennett
,
L. Hondeghem
,
H. Kesteloot
European Journal of Clinical Pharmacology
2004
Corpus ID: 36101721
SummaryThe antiarrhythmic efficacy of transcainide has been studied in 41 patients. It abolished ventricular arrhythmias in 10…
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1992
1992
Clinical and electrophysiologic studies of R61748 (transcainide): a new class Ic antiarrhythmic drug.
X. Yang
,
T. Yu
,
H. Kesteloot
Acta Cardiologica
1992
Corpus ID: 43767092
The electrophysiology and antiarrhythmic efficacy of R61748, a 4-OH metabolite of R54718 (transcainide), have been studied in…
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1988
1988
Slowly Developing Activation Block of Cardiac Sodium Channels by a Lidocaine Analog, Transcainide
E. Carmeliet
Journal of Cardiovascular Pharmacology
1988
Corpus ID: 22522726
The working mechanism of Na+ channel block by a lidocaine analog, transcainide, was investigated. The Na+ channel block was…
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1987
1987
Sodium Channel Block by a Potent, New Antiarrhythmic Agent, Transcainide, in Guinea Pig Ventricular Myocytes
P. Bennett
,
R. Stroobandt
,
H. Kesteloot
,
L. Hondeghem
Journal of Cardiovascular Pharmacology
1987
Corpus ID: 25191692
Transcainidse is a new lidocaine analog that has been shown to suppress a range of cardiac arrhythmias in an initial clinical…
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1987
1987
Electrophysiologic, antiarrhythmic and hemodynamic effects of transcainide.
E. Carmeliet
,
P. Janssen
,
+6 authors
R. Xhonneux
Archives internationales de pharmacodynamie et de…
1987
Corpus ID: 31442590
Transcainide was selected as an antiarrhythmic drug with potential clinical application. In isolated dog, sheep and rabbit…
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