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thymus development

The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Zebrafish mutants with disrupted early T‐cell and thymus development identified in early pressure screen
Generation of mature T lymphocytes requires an intact hematopoietic stem cell compartment and functional thymic epithelium. We… 
Review
2006
Review
2006
Trafficking on serpentines: molecular insight on how maturating T cells find their winding paths in the thymus
Summary:  Maintenance of the peripheral T‐cell pool throughout the life requires uninterrupted generation of T cells. The… 
Review
2002
Review
2002
Transgenic analysis of thymocyte signal transduction
This review examines the value of transgenic studies in mice for the genetic dissection of signal-transduction pathways relevant… 
2002
2002
Expression and mutation analysis of BRUNOL3, a candidate gene for heart and thymus developmental defects associated with partial monosomy 10p
Partial monosomy 10p is a rare chromosomal aberration. Patients often show symptoms of the DiGeorge/velocardiofacial syndrome… 
Review
2001
Review
2001
Signal transduction in thymus development.
Reciprocal interaction between bone marrow derived lymphoid precursor cells and the thymic environment leads, through a series of… 
Highly Cited
1993
Highly Cited
1993
Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes.
To evaluate the biologic potential of T cell-specific TNF production in vivo, we have generated transgenic mice constitutively… 
1991
1991
Gamma delta T cells expressing CD8 or CD4low appear early in murine foetal thymus development.
Three-colour flow cytometry was used to study the distribution of TCR gamma delta+ cells among CD4+CD8-, CD4-CD8+, CD4+CD8+, and… 
1984
1984
Characterization of stromal cell populations in the developing thymus of normal and nude mice
The role of the thymic stromal components in T cell maturation has been investigated by compairing stromal composition in the… 
Highly Cited
1983
Highly Cited
1983
Flow microfluorometric analysis of mouse thymus development in vivo and in vitro
The phenotypic properties of lymphoid cells in the developing embryonic thymus were characterized using monoclonal antibodies and… 
1978
1978
Embryonic mouse thymus development: stem cell entry and differentiation.
The entry and subsequent division and differentiation of blood-borne stem cells within the embryonic thymus has been studied in a… 
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