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thymidylate

 
National Institutes of Health

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Review
2008
Review
2008
In spite of their common hypersaline environment, halophilic archaea are surprisingly different in their nutritional demands and… Expand
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Highly Cited
2008
Highly Cited
2008
Tetrahydrofolate (THF) polyglutamates are a family of cofactors that carry and chemically activate one-carbon units for… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE A 6 bp deletion polymorphism in the thymidylate synthase (TS) gene was investigated in order to determine its function… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryAphidicolin, a specific inhibitor of DNA polymerase α, is known to induce chromosomal aberrations. At concentrations that… Expand
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Highly Cited
2002
Highly Cited
2002
Folate-dependent one-carbon metabolism is required for the synthesis of purines and thymidylate and for the remethylation of… Expand
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Highly Cited
1997
Highly Cited
1997
Folate is essential for the de novo biosynthesis of purines and thymidylate, and is an important mediator in the transfer of… Expand
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Highly Cited
1997
Highly Cited
1997
Structural comparison of thymidylate kinase complexed with either dTMP or with AZTMP suggests that the low phosphorylation rate… Expand
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Highly Cited
1986
Highly Cited
1986
The thymidine analog 3'-azido-3'-deoxythymidine (BW A509U, azidothymidine) can inhibit human immunodeficiency virus (HIV… Expand
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Highly Cited
1982
Highly Cited
1982
We have examined the genetic and biochemical consequences of thymidylate stress in haploid and diploid strains of the simple… Expand
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Highly Cited
1973
Highly Cited
1973
The suppression of DNA synthesis in host and tumor tissues by methotrexate has been monitored in mice by determining the in vivo… Expand
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