thymidylate synthase (FAD) activity

Known as: 5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity, flavin dependent thymidylate synthase activity, ThyX activity 
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+. [EC:2.1.1.148]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2012
0120022012

Papers overview

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2012
2012
ThyX, a flavin-dependent thymidylate synthase that is involved in the synthesis of dTMP from dUMP, is a promising target for the… (More)
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2009
2009
Flavin-dependent thymidylate synthases (FDTS) catalyze the production of dTMP from dUMP and N(5),N(10)-methylene-5,6,7,8… (More)
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2007
2007
Although flavin-dependent ThyX proteins show thymidylate synthase activity in vitro and functionally complement thyA defects in… (More)
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2006
2006
The novel flavin-dependent thymidylate synthase, ThyX, is absent in humans but several pathogenic bacteria depend exclusively on… (More)
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Highly Cited
2002
Highly Cited
2002
Although deoxythymidylate cannot be provided directly by ribonucleotide reductase, the gene encoding thymidylate synthase ThyA is… (More)
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