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thuggacin A

 
National Institutes of Health

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Macrolides

Papers overview

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2016
2016
Total Synthesis of a Diacetonide Derivative of Thuggacin A.
A highly stereoselective total synthesis of the diacetonide derivative of the antibiotic thuggacin A has been described. The… Expand
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2008
2008
Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum.
Since 1993, when the World Health Organization declared tuberculosis “a global health emergency”, there has been new impetus to… Expand
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2007
2007
Thuggacins, macrolide antibiotics active against Mycobacterium tuberculosis: isolation from myxobacteria, structure elucidation, conformation analysis and biosynthesis.
Two novel antibiotics, thuggacin A (1) and B (2), were isolated from the myxobacterium Sorangium cellulosum. 1 and 2 are unique… Expand
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2007
2007
The Thuggacins, Novel Antibacterial Macrolides from Sorangium cellulosum Acting against Selected Gram-positive Bacteria
In our screening program we found an activity against some Gram-positive bacteria, including mycobacteria in the culture… Expand
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