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thrombopoietin-mediated signaling pathway

Known as: THPO signaling pathway, THPO/MPL signaling pathway, thrombopoietin receptor signaling pathway 
A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with… 
National Institutes of Health

Papers overview

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2018
2018
A network map of thrombopoietin signaling
Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a cytokine involved in the production… 
Review
2017
Review
2017
Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis
Megakaryopoiesis is an original and complex cell process which leads to the formation of platelets. The homeostatic production of… 
Review
1993
Review
1993
Conformational aspects of the muscarinic receptor interactions of bicyclic isoxazole ester bioisosteres of arecoline.
3-Methoxy-4,5,6,7-tetrahydroisoxazolo [4,5-c]pyridine (O-Me-THPO) and O,5-di-Me-THPO are conformationally restricted bioisosteres… 
1986
1986
A novel class of conformationally restricted heterocyclic muscarinic agonists.
A series of conformationally restricted compounds containing the 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol (THPO) skeleton… 
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